3214-57-1

Basic information

• Product Name: 2,5-Cyclohexadiene-1,4-dione, 2-methoxy-3,5-dimethyl-
• Synonyms: 2-methoxy-3,5-dimethyl-[1,4]benzoquinone;3,5-dimethyl-2-methoxybenzoquinone;2-Methoxy-3,5-dimethyl-benzochinon-(1,4);2-methoxy-3,5-dimethylbenzoquinone;2-Methoxy-3,5-dimethyl-[1,4]benzochinon;3,5-dimethyl-2-methoxy-p-benzoquinone
• CAS NO: 3214-57-1
• Molecular Formula: C9H10O3
• Molecular Weight: 166.177
• Mol File: 3214-57-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 55 - 56 °C
• CAS DataBase Reference: 2,5-Cyclohexadiene-1,4-dione, 2-methoxy-3,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Cyclohexadiene-1,4-dione, 2-methoxy-3,5-dimethyl-(3214-57-1)
• EPA Substance Registry System: 2,5-Cyclohexadiene-1,4-dione, 2-methoxy-3,5-dimethyl-(3214-57-1)

Safety Data

• Hazardous Substances Data: 3214-57-1(Hazardous Substances Data)

Usage

Physical state

Yellow crystalline solid

Odor

Distinct

Solubility

Insoluble in water

Uses

Synthesis of pharmaceuticals and organic compounds; antioxidant properties in skincare and cosmetic products; intermediate in the production of various chemical compounds

Potential applications

Organic chemistry research and development

Upstream product

• 41168-76-7 1,3-dimethyl-2,4,5-triacetoxybenzene 
• 527-61-7 2,6-dimethyl-1,4-benzoquinone 
• 92421-42-6 1,3-dimethyl-2,4,5-trimethoxybenzene 
• 29769-77-5 3-methoxy-4-methyl-3-cyclobutene-1,2-dione 
• 74-99-7 prop-1-yne 
• 2785-85-5 2-methoxy-3,5-dimethylphenol 
• 2913-40-8 3,5-dimethyl-2-hydroxy-p-benzoquinone 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 1431987-18-6 8-(5-methoxy-2,4-dimethyl-3,6-dioxocyclohexa-1,4-dienyl)octyl nitrate 
• 1431987-13-1 6-(5-methoxy-2,4-dimethyl-3,6-dioxo cyclohexa-1,4-dienyl)hexyl nitrate 
• 1431987-16-4 10-(5-methoxy-2,4-dimethyl-3,6-dioxocyclohexa-1,4-dienyl)decyl nitrate 

Relevant articles and documents

QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS FOR OPHTHALMIC USE

The present invention relates to novel nitric oxide donor compounds for the use in the treatment and/or prophylaxis of hypertensive glaucoma, normotensive glaucoma and ocular hypertension.

Synthesis and characterization of mitoQ and idebenone analogues as mediators of oxygen consumption in mitochondria

Analogues of mitoQ and idebenone were synthesized to define the structural elements that support oxygen consumption in the mitochondrial respiratory chain. Eight analogues were prepared and fully characterized, then evaluated for their ability to support oxygen consumption in the mitochondrial respiratory chain. While oxygen consumption was strongly inhibited by mitoQ analogues 2-4 in a chain length-dependent manner, modification of idebenone by replacement of the quinone methoxy groups by methyl groups (analogues 6-8) reduced, but did not eliminate, oxygen consumption. Idebenone analogues 6-8 also displayed significant cytoprotective properties toward cultured mammalian cells in which glutathione had been depleted by treatment with diethyl maleate.

Convergent, High-Yield, Regioselective Synthesis of Substituted Benzoquinones from Maleoylcobalt Complexes and Alkynes

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