32151-01-2 Usage
General Description
(1R,2S)-(+)-2-Amino-1-indanol hydrochloride is a chemical compound with the molecular formula C9H12ClNO. It is a chiral, biologically active molecule with potential applications in pharmaceuticals and organic synthesis. (1R,2S)-(+)-2-Amino-1-indanol hydrochloride contains an amino group and a hydroxyl group, making it versatile for chemical reactions and drug development. The hydrochloride salt form enhances the stability and solubility of the compound, making it more suitable for various applications. Its stereochemical arrangement, as indicated by the (1R,2S) designation, is important for its biological activity and potential therapeutic use. Overall, (1R,2S)-(+)-2-Amino-1-indanol hydrochloride is an important chemical with promising applications in the field of pharmaceuticals and organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 32151-01-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,1,5 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 32151-01:
(7*3)+(6*2)+(5*1)+(4*5)+(3*1)+(2*0)+(1*1)=62
62 % 10 = 2
So 32151-01-2 is a valid CAS Registry Number.
32151-01-2Relevant articles and documents
Efficient diastereoselective synthesis of cis-2-amino-1-indanol derivatives and cis- and trans-1-amino-2-indanol via Pd-catalyzed hydrogenation
Nguyen, Thi Ha,Ma, Eunsook
supporting information, p. 3717 - 3728 (2021/11/01)
(±)-cis-2-amino-1-indanol was diastereoselectively synthesized from 1,2-indanedion-2-oxime in ethanol at 25 °C under 10% Pd/C-catalyzed hydrogenation conditions. Under the same hydrogenation condition, 1,2-indanedion-2-oxime and their derivatives having one and/or two electron-donating groups in aliphatic or aromatic part of indanyl ring were diastereoselectively reduced to racemic cis-2-amino-1-indanol derivatives. From 1,2-indanedion-1-oxime, (±)-trans-1-amino-2-indanol was obtained in ethanol at 25 °C over a 10% Pd/BaSO4 catalyst. In contrast, the 10% Pd/BaSO4-catalyzed hydrogenation reaction in ethanol at 45 °C afforded cis-1-hydroxyamino-2-indanol from 1,2-indanedion-1-oxime, followed by reduction to form (±)-cis-1-amino-2-indanol. The diastereoselectivity of β-aminoindanols was dependent on the Pd catalyst, reaction temperature, and pH of the reaction medium.
