32189-20-1 Usage
Description
(1R,3S)-1,3-Bis(acetylamino)cyclohexane is a chemical compound with the molecular formula C12H20N2O2. It is a stereoisomer of 1,3-Bis(acetylamino)cyclohexane, with the (1R,3S) configuration. (1R,3S)-1,3-Bis(acetylamino)cyclohexane features a unique cyclic structure and the presence of acetylamino groups, making it a versatile intermediate for the synthesis of various pharmaceuticals and biologically active compounds.
Uses
Used in Organic Synthesis:
(1R,3S)-1,3-Bis(acetylamino)cyclohexane is used as a reagent and building block in organic synthesis for the production of diverse chemical compounds with potential biological activities.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (1R,3S)-1,3-Bis(acetylamino)cyclohexane is utilized as a key intermediate for the synthesis of pharmaceuticals, contributing to the development of new drugs with therapeutic applications.
Used in Materials Science:
(1R,3S)-1,3-Bis(acetylamino)cyclohexane may also have applications in materials science, where its structural properties could be employed in the development of new materials with specific properties and functionalities.
Check Digit Verification of cas no
The CAS Registry Mumber 32189-20-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,1,8 and 9 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 32189-20:
(7*3)+(6*2)+(5*1)+(4*8)+(3*9)+(2*2)+(1*0)=101
101 % 10 = 1
So 32189-20-1 is a valid CAS Registry Number.
32189-20-1Relevant articles and documents
Discovery of cyclopentane- and cyclohexane-trans-1,3-diamines as potent melanin-concentrating hormone receptor 1 antagonists
Giordanetto, Fabrizio,Karlsson, Olle,Lindberg, Jan,Larsson, Lars-Olof,Linusson, Anna,Evertsson, Emma,Morgan, David G.A.,Inghardt, Tord
, p. 4232 - 4241 (2008/12/21)
We herein report the optimization of cyclopentane- and cyclohexane-1,3-diamine derivatives as novel and potent MCH-R1 antagonists. Structural modifications of the 2-amino-quinoline and thiophene moieties found in the initial lead compound served to improve its metabolic stability profile and MCH-R1 affinity, and revealed unprecedented SAR when compared to other 2-amino-quinoline-containing MCH-R1 antagonists.
