32245-50-4Relevant articles and documents
Re-examination of the synthesis of 7,8-dimethoxy-2-methyl-3-(4',5'-methylenedioxy-2'-vinylphenyl)isocarbos tyril
Ishii,Takeda,Ogata,Hanaoka,Harayama
, p. 2712 - 2714 (1991)
Oxidation of the enamine (6) to the isocarbostyril (7) was re-examined. Simply stirring a dimethylformamide (DMF) solution of 6 provided 7 with good reproducibility, in the presence of KCN under an oxygen atmosphere. The structure of the chloroform adduct (8) was determined by an X-ray analysis.