32253-75-1 Usage
Description
5-BROMO-N-(CARBOXYMETHYL)ANTHRANILIC ACID is a yellow crystalline powder that is utilized in various chemical synthesis processes due to its unique chemical properties.
Uses
Used in Chemical Synthesis:
5-BROMO-N-(CARBOXYMETHYL)ANTHRANILIC ACID is used as a key intermediate for the synthesis of various pharmaceutical compounds and other specialty chemicals. Its unique structure and reactivity make it a valuable building block in the development of new molecules with potential applications in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-BROMO-N-(CARBOXYMETHYL)ANTHRANILIC ACID is used as a starting material for the development of new drugs. Its chemical properties allow for the creation of novel therapeutic agents that can target specific biological pathways, potentially leading to more effective treatments for various diseases and conditions.
Used in Research and Development:
5-BROMO-N-(CARBOXYMETHYL)ANTHRANILIC ACID is also used in research and development laboratories for the study of its chemical properties and potential applications. Scientists and researchers can use this compound to explore new reaction pathways, develop innovative synthetic methods, and discover new compounds with unique properties and potential uses.
Used in Dye and Pigment Industry:
Due to its yellow crystalline nature, 5-BROMO-N-(CARBOXYMETHYL)ANTHRANILIC ACID can be used as a starting material for the synthesis of dyes and pigments. Its color properties can be exploited to create new dyes with specific color characteristics, which can be used in various applications such as textiles, plastics, and printing inks.
Used in Agricultural Industry:
5-BROMO-N-(CARBOXYMETHYL)ANTHRANILIC ACID may also find applications in the agricultural industry, where it can be used as a starting material for the synthesis of agrochemicals, such as herbicides, insecticides, and fungicides. Its unique chemical properties can be harnessed to develop new compounds with improved efficacy and selectivity, leading to more sustainable and environmentally friendly agricultural practices.
Check Digit Verification of cas no
The CAS Registry Mumber 32253-75-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,2,5 and 3 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 32253-75:
(7*3)+(6*2)+(5*2)+(4*5)+(3*3)+(2*7)+(1*5)=91
91 % 10 = 1
So 32253-75-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H8BrNO4/c10-5-1-2-7(11-4-8(12)13)6(3-5)9(14)15/h1-3,11H,4H2,(H,12,13)(H,14,15)/p-2
32253-75-1Relevant articles and documents
Indirubin Derivatives as Dual Inhibitors Targeting Cyclin-Dependent Kinase and Histone Deacetylase for Treating Cancer
An, Jianxiong,Cao, Zhuoxian,Gu, Zhicheng,He, Bin,Li, Yan,Li, Yongjun,Lin, Hening,Lin, Shuxian,Liu, Ting,Wang, Jie,Wang, Pan,Yang, Fenfen,Zhao, Yonglong
, p. 15280 - 15296 (2021/10/25)
To utilize the unique scaffold of a natural product indirubin, we herein adopted the strategy of combined pharmacophores to design and synthesize a series of novel indirubin derivatives as dual inhibitors against cyclin-dependent kinase (CDK) and histone deacetylase (HDAC). Among them, the lead compound 8b with remarkable CDK2/4/6 and HDAC6 inhibitory activity of IC50 = 60.9 ± 2.9, 276 ± 22.3, 27.2 ± 4.2, and 128.6 ± 0.4 nM, respectively, can efficiently induce apoptosis and S-phase arrest in several cancer cell lines. In particular, compound 8b can prevent the proliferation of a non-small-cell lung cancer cell line (A549) through the Mcl-1/XIAP/PARP axis, in agreement with the unique modes of action of the combined agents of HDAC inhibitors and CDK inhibitors. In an A549 xerograph model, compound 8b showed significant antitumor efficacy correlated with its dual inhibition. Our data demonstrated that compound 8b as a single agent could be a promising drug candidate for cancer therapy in combination with CDK and HDAC inhibitors.
AZAINDOLE-INDOLE COUPLED DERIVATIVES, PREPARATION METHODS AND USES THEREOF
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Page/Page column 13, (2010/04/25)
A novel class of azaindole-indole coupled derivatives, their preparation methods, pharmaceutical compositions containing the same and the uses thereof. The common structural feature of these derivatives is that they are coupled by azaindole and indole bi-molecule at different positions, forming extended pi-conjugated systems. Such derivatives inhibited cell growth and proliferation by various mechanisms. The present compounds have improved solubility, increased bioavailability, and thus have enhanced drug actions, and reduced medical dosages and undesired responses.
A practical and efficient vilsmeier synthesis of 3-chloroindole-2- carboxaldehydes
Li,Hu,Chen,Su
experimental part, p. 479 - 484 (2011/02/22)
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