3226-39-9

Basic information

• Product Name: 1,4-dichloro-2-thiocyanatobenzene
• Synonyms: 1,4-dichloro-2-thiocyanatobenzene
• CAS NO: 3226-39-9
• Molecular Weight: 204.08
• Mol File: 3226-39-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,4-dichloro-2-thiocyanatobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-dichloro-2-thiocyanatobenzene(3226-39-9)
• EPA Substance Registry System: 1,4-dichloro-2-thiocyanatobenzene(3226-39-9)

Safety Data

• Hazardous Substances Data: 3226-39-9(Hazardous Substances Data)

Upstream product

• 5858-18-4 2,5-dichlorbenzenethiol 
• 95-82-9 2,5 dichloroaniline 
• 333-20-0 potassium thioacyanate 

Downstream Products

• 3097-21-0 1,3-dimethyl-1,3-dihydrobenzimidazol-2-one 
• 5335-80-8 di(2,5-dichlorophenyl)disulfide 
• 398-75-4 (2,5-dichlorophenyl) trifluoromethyl sulfide 

Relevant articles and documents

General and practical formation of thiocyanates from thiols

A new method for the cyanation of thiols and disulfides using cyanobenziodoxol(on)e hypervalent iodine reagents is described. Both aliphatic and aromatic thiocyanates can be accessed in good yields in a few minutes at room temperature starting from a broad range of thiols with high chemioselectivity. The complete conversion of disulfides to thiocyanates was also possible. Preliminary computational studies indicated a low energy concerted transition state for the cyanation of the thiolate anion or radical. The developed thiocyanate synthesis has broad potential for various applications in synthetic chemistry, chemical biology and materials science.