32268-30-7Relevant articles and documents
Synthetic methods for Gramniphenols F and G, Cicerfuran, Morunigrol C and its Derivative
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Paragraph 0017; 0018, (2017/07/11)
The present invention relates to a method for preparing natural benzofurans including gramniphenol F, gramniphenol G, morunigrol C and 3andprime;,5andprime;-di-O-methyl analogues thereof and cicerfuran by using 2,4-dihydroxybenzaldehyde, 5-bromoresorcinol and sesamol. In the method according to the present invention, region-selective prenylation, Ramirez gem-dibromo olefination, Miyaura borylation and Suzuki coupling are used. In addition, the compounds were determined for anti-inflammatory effects through a test for production of nitrogen oxide in liposaccharide-induced RAW-264.7 macrophages. All of the compounds show weak to medium (16-42%) inhibitory activities, are not toxic and have an IC_50 value of 9.1 to 25.2 andmu;M.COPYRIGHT KIPO 2017
Facile synthesis of licochalcone C
Kim, Cheol Gi,Jeon, Jae-Ho,Seo, Young Hwa,Jun, Jong-Gab
, p. 1996 - 1998 (2014/09/17)
Licochalcone C was synthesized from commercially available 2,4-dihydroxybenzaldehde by using regioselective Al2O 3-mediated C-prenylation followed by conventional Claisen-Schmidt condensation in basic condition.
THERAPEUTIC AGENT
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Page/Page column 64, (2010/11/08)
A therapeutic agent and prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for an insulin-mimetic action, a food, beverage and feed, an agent for enhancing glucose uptake into a cell, and an agent for inducing differentiation into an adipocyte, characterized in that each comprises as an effective ingredient at least one compound selected from the group consisting of a chalcone compound, an acetophenone compound, a coumarin compound, a phthalide compound, derivatives thereof, and pharmacologically acceptable salts thereof.