32294-42-1

Basic information

• Product Name: Thiourea, N-(6-methoxy-2-benzothiazolyl)-N'-phenyl-
• Synonyms: 1-(6-methoxybenzo[d]thiazol-2-yl)-3-phenylthiourea
• CAS NO: 32294-42-1
• Molecular Formula: C15H13N3OS2
• Molecular Weight: 315.42
• Mol File: 32294-42-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Thiourea, N-(6-methoxy-2-benzothiazolyl)-N'-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiourea, N-(6-methoxy-2-benzothiazolyl)-N'-phenyl-(32294-42-1)
• EPA Substance Registry System: Thiourea, N-(6-methoxy-2-benzothiazolyl)-N'-phenyl-(32294-42-1)

Safety Data

• Hazardous Substances Data: 32294-42-1(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 756476-97-8 N-(6-methoxybenzo[d]thiazol-2-yl)-1H-imidazole-1-carbothioamide 
• 1747-60-0 6-methoxybenzothiazol-2-ylamine 
• 6160-65-2 1,1'-Thiocarbonyldiimidazole 
• 103-72-0 phenyl isothiocyanate 

Downstream Products

• 140190-25-6 {Mn(C₆H₅NC(S)NH(C₇H₃NSOCH₃))2(H₂O)2} 
• 72128-95-1 N-isopropyl-N'-(6-methoxy-benzothiazol-2-yl)-N''-phenyl-guanidine 

Relevant articles and documents

Molecular Iodine-Promoted [3 + 2] Oxidative Cyclization for the Synthesis of Heteroarene-Fused [1,2,4] Thiadiazoles/Selenadiazoles

Two new classes of heteroarene-fused [1,2,4]thiadiazole and [1,2,4]selenadiazole are synthesized through the iodine-mediated [3 + 2] oxidative cyclization of 2-aminoheteroarenes and isothiocyanates/isoselenocyanates. This oxidative [3 + 2] annulation stra

Identification of small-molecule inhibitors of the Aβ-ABAD interaction

The interaction of amyloid beta peptide (Aβ) and Aβ-binding alcohol dehydrogenase (ABAD) was recently implicated in the pathogenesis of Alzheimer's disease (AD). Using an ELISA-based screening assay, we identified frentizole, an FDA-approved immunosuppressive drug, as a novel inhibitor of the Aβ-ABAD interaction. Analysis of the frentizole structure-activity relationship led to identification of a novel benzothiazole urea with a 30-fold improvement in potency.