3232-26-6

Basic information

• Product Name: 6-butyl-1,3,5-triazine-2,4-diamine
• Synonyms: 1,3,5-triazine-2,4-diamine, 6-butyl-; 6-Butyl-1,3,5-triazine-2,4-diamine
• CAS NO: 3232-26-6
• Molecular Formula: C₇H₁₃N₅
• Molecular Weight: 167.2116
• Mol File: 3232-26-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 419.9°C at 760 mmHg
• Flash Point: 237.2°C
• Density: 1.198g/cm³
• Vapor Pressure: 2.93E-07mmHg at 25°C
• Refractive Index: 1.601
• CAS DataBase Reference: 6-butyl-1,3,5-triazine-2,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-butyl-1,3,5-triazine-2,4-diamine(3232-26-6)
• EPA Substance Registry System: 6-butyl-1,3,5-triazine-2,4-diamine(3232-26-6)

Safety Data

• Hazardous Substances Data: 3232-26-6(Hazardous Substances Data)

Upstream product

• 55034-34-9 valeryl-guanidine 
• 593-85-1 diguanidine carbonate 
• 109-52-4 valeric acid 

Relevant articles and documents

2,4,6-trisubstituted-1,3,5-s-triazine compound and preparation and application thereof

The invention provides a 2,4,6-trisubstituted-1,3,5-s-triazine compound as well as preparation and application thereof, and biguanide or dimethyl biguanide hydrochloride is used as an initial raw material to react with a cyano compound under an alkaline condition to prepare the 2,4,6-trisubstituted-1,3,5-s-triazine compound. The invention provides a simple and convenient synthetic method of a 2,4,6-trisubstituted-1,3,5-s-triazine compound, and the compound provided by the invention can be applied to preparation of an anti-myelogenous leukemia medicine, namely an enasidenib medicine. Compared with the prior art, the method for preparing the enasidenib has the advantages that two-step reaction is reduced, the use of a halogenating reagent is avoided, and the method is a green and environment-friendly chemical process. The structural formula I is shown in the specification.