32376-95-7

Basic information

• Product Name: Benzenesulfonic acid, 2-phenylethyl ester
• CAS NO: 32376-95-7
• Molecular Formula: C14H14O3S
• Molecular Weight: 262.329
• Mol File: 32376-95-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenesulfonic acid, 2-phenylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonic acid, 2-phenylethyl ester(32376-95-7)
• EPA Substance Registry System: Benzenesulfonic acid, 2-phenylethyl ester(32376-95-7)

Safety Data

• Hazardous Substances Data: 32376-95-7(Hazardous Substances Data)

Upstream product

• 60-12-8 2-phenylethanol 
• 593-56-6 N-methoxylamine hydrochloride 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 1739-00-0 (N-phenyl)phenylethylamine 
• 98-11-3 benzenesulfonic acid 
• 4484-20-2 aniline benzenesulfonate 
• 2405-59-6 N-(2-phenylethyl)-4-methoxyaniline 
• 1739-04-4 N-(4-chlorophenyl)-N-(2-phenylethyl)amine 
• 1739-02-2 N-(4-methylphenyl)-N-(2-phenylethyl)amine 

Relevant articles and documents

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Deoxyalkoxyamination of Alcohols for the Synthesis of N-Alkoxy-N-alkylbenzenesulfonamides

A novel protocol for the deoxyalkoxyamination of alcohols has been developed, using N-alkoxybenzenesulfonimide (NOSI) as both a sulfonyl transfer reagent and an alkoxyamine source, accessing a diverse range of N-alkoxy-N-alkylbenzenesulfonamides with excellent isolated yields. This method is characterized by metal-free reaction, scalability, and waste-balance. Chiral substrates are converted with excellent levels of stereochemical inversion. NOSI could be generated in situ during the reaction as a stable reagent if a three-component one-pot reaction was designed. Exploiting this approach to run intramolecular reactions offered various N-protected isoxazolidines. In addition, valuable O-alkyl hydroxylamines (or isoxazolidines) were obtained through a neutral strategy of desulfonylation of the products.