324037-46-9

Basic information

• Product Name: 5-Pyrimidinecarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-6-methyl-2-(methylthio)-, ethyl ester
• CAS NO: 324037-46-9
• Molecular Formula: C16H20N2O3S
• Molecular Weight: 320.412
• Mol File: 324037-46-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 5-Pyrimidinecarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-6-methyl-2-(methylthio)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-6-methyl-2-(methylthio)-, ethyl ester(324037-46-9)
• EPA Substance Registry System: 5-Pyrimidinecarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-6-methyl-2-(methylthio)-, ethyl ester(324037-46-9)

Safety Data

• Hazardous Substances Data: 324037-46-9(Hazardous Substances Data)

Upstream product

• 113697-57-7 5-(ethoxycarbonyl)-4-(4-methoxyphenyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-thione 
• 77-78-1 dimethyl sulfate 
• 123-11-5 4-methoxy-benzaldehyde 
• 141-97-9 ethyl acetoacetate 
• 14527-26-5 2-methylisothiourea sulphate 
• 74-88-4 methyl iodide 

Downstream Products

• 1117816-30-4 C₃₁H₂₅ClN₄O₅ 
• 1236204-32-2 ethyl 4-(4-methoxyphenyl)-6-methyl-2-(methylthio)pyrimidine-5-carboxylate 
• 1412900-78-7 ethyl 3-(5-bromo-benzofuran-2-carbonyl)-5-(4-methoxyphenyl)-7-methyl-1-phenyl-1,5-dihydro-[1,2,4]triazolo[4,3-a]pyrimidine-6-carboxylate 

Relevant articles and documents

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Novel pyrimidinic selenoureas were synthesized and evaluated against tumour and normal cell lines. Among these, the compound named 3j initially showed relevant cytotoxicity and selectivity for tumour cells. Three analogues of 3j were designed and synthesi

Synthesis, molecular docking, and cardioprotective activity of 2-methylthio-1,4-dihydropyrimidines

A series of 2-methylthio-1,4-dihydropyrimidine derivatives (IIa-IIl) were synthesized in good yields by alkylation of 1,2,3,4-tetrahydropyrimidines (Ia-Il) with methyl iodide in the presence of pyridine. Their structures were confirmed by elemental analys

Mild and efficient oxidative aromatization of 4-substituted-1,4- dihydropyrimidines using (diacetoxyiodo)benzene

(Chemical Equation Presented) 4-Alkyl or aryl-1,4-dihydropyrimidines were readily oxidized by (diacetoxyiodo)benzene under mild reaction conditions to the corresponding pyrimidine derivatives in good to excellent yields.