325154-26-5Relevant articles and documents
A aliskiren or its salt separation and analysis method
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, (2017/08/25)
The invention relates to a separation analysis method using polysaccharide derivative-bonded and coated silica as a stationary phase and an organic solvent as a mobile phase for separation analysis of aliskiren and isomers thereof, effective separation of the aliskiren and isomers thereof can be realized, and the separation analysis method has the important meaning to the product quality control.
Investigation of a kumada cross coupling reaction for large-scale production of (2 S, 7 R, E)-2-isopropyl-7-(4-methoxy-3-(3-methoxypropoxy)benzyl)- N, N,8-trimethylnon-4-enamide
Gangula, Srinivas,Neelam, Uday Kumar,Baddam, Sudharkar Reddy,Dahanukar, Vilas H.,Bandichhor, Rakeshwar
, p. 470 - 475 (2015/03/30)
An investigation into the Kumada cross coupling reaction was conducted by developing a reliable, efficient procedure for the Grignard reagent and its subsequent cross coupling reaction. Safe Mg metal activation as well as a moisture-free system was create
AN IMPROVED PROCESS FOR THE PREPARATION OF ALISKIREN
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, (2013/12/03)
The present invention relates to an improved process for the preparation of renin inhibitor Aliskiren intermediates of Formula-II and further conversion into Aliskiren and its pharmaceutically acceptable salts.