325457-74-7Relevant articles and documents
Design and synthesis of aminophenol-based factor Xa inhibitors
Wu, Shung,Guilford, William J,Chou, Yuo-Ling,Griedel, Brian D,Liang, Amy,Sakata, Steve,Shaw, Kenneth J.,Trinh, Lan,Xu, Wei,Zhao, Zuchun,Morrissey, Michael M.
, p. 1307 - 1310 (2007/10/03)
A novel potent and selective aminophenol scaffold for fXa inhibitors was developed from a previously reported benzimidazole-based naphthylamidine template. The aminophenol template is more synthetically accessible than the benzimidazole template, which si