325480-40-8 Usage
Description
(1R,2R)-2-((Benzyloxy)Methyl)cyclopent-3-enol is a complex organic compound characterized by its unique molecular structure, which features a cyclopentane ring with a 3-enol functional group and a benzyloxymethyl group attached to the 2nd carbon. (1R,2R)-2-((Benzyloxy)Methyl)cyclopent-3-enol is known for its specific stereochemistry, with the R configuration at both the 1st and 2nd carbon positions.
Uses
Used in Pharmaceutical Industry:
(1R,2R)-2-((Benzyloxy)Methyl)cyclopent-3-enol is used as a key reactant for the synthesis of carbocyclic deoxyguanosine analogs. These analogs possess potent and selective anti-hepatitis B virus properties, making them valuable in the development of new antiviral drugs to combat hepatitis B.
(1R,2R)-2-((Benzyloxy)Methyl)cyclopent-3-enol's unique structure and reactivity enable the creation of novel therapeutic agents that can specifically target and inhibit the replication of the hepatitis B virus, offering a potential treatment option for patients suffering from this disease.
Check Digit Verification of cas no
The CAS Registry Mumber 325480-40-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,5,4,8 and 0 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 325480-40:
(8*3)+(7*2)+(6*5)+(5*4)+(4*8)+(3*0)+(2*4)+(1*0)=128
128 % 10 = 8
So 325480-40-8 is a valid CAS Registry Number.
325480-40-8Relevant articles and documents
N-O bond as a glycosidic-bond surrogate: Synthetic studies toward polyhydroxylated N-alkoxypiperidines
Malik, Ga?lle,Ferry, Angélique,Guinchard, Xavier,Cresteil, Thierry,Crich, David
supporting information, p. 2168 - 2179 (2013/03/29)
A series of novel polyhydroxylated N-alkoxypiperidines has been synthesized by ring-closing double reductive amination (DRA) of highly functionalized 1,5-dialdehydes with various hydroxylamines. The required saccharide-based dialdehydes were prepared efficiently from sodium cyclopentadienylide in seven steps. A two-step protocol has been developed for the DRA; it led, after deprotection, to isofagomine, 3-deoxyisofagomine, and numerous other N-alkoxy analogues. The barrier to inversion in these polyhydroxylated N-alkoxypiperidine derivatives was found by variable-temperature NMR methods to be approximately 15 kcal mol-1. With the exception of N-hydroxyisofagomine itself, none of the compounds prepared showed significant inhibitory activity against sweet almond β-glucosidase. Copyright
Enantioselective synthesis of optically active carbocyclic sugars
Gathergood,Knudsen,Jorgensen
, p. 1014 - 1017 (2007/10/03)
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