325484-84-2Relevant articles and documents
Analogues of glycosphingolipids and glycerolipids suitable for conjugation to gold- and amino-functionalised surfaces
Ohlsson, J?rgen,Magnusson, G?ran
, p. 9975 - 9984 (2000)
A general synthesis of analogues of natural lipids, (i.e. lactosylceramide, globotriasylceramide, and phosphatidylcholine) where one of the alkyl chains carries a terminal thiol- or carboxyl functionality, is described. The lipids were prepared by N- or O-acylation of sphingosine or monoacylglycerol derivatives. These lipids are suitable for anchoring to gold- or amino-functionalised surfaces, thus creating mimics of a cell membrane for use in the study of protein-carbohydrate interaction. (C) 2000 Elsevier Science Ltd.