32560-53-5

Basic information

• Product Name: 4-(2-AMinoethyl)-2-chlorophenol
• Synonyms: 4-(2-AMinoethyl)-2-chlorophenol
• CAS NO: 32560-53-5
• Molecular Formula: C₈H₁₀ClNO
• Molecular Weight: 171.6241
• Mol File: 32560-53-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 283.011°C at 760 mmHg
• Flash Point: 124.961°C
• Appearance: /
• Density: 1.259g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.592
• PKA: 8.09±0.31(Predicted)
• CAS DataBase Reference: 4-(2-AMinoethyl)-2-chlorophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-AMinoethyl)-2-chlorophenol(32560-53-5)
• EPA Substance Registry System: 4-(2-AMinoethyl)-2-chlorophenol(32560-53-5)

Safety Data

• Hazardous Substances Data: 32560-53-5(Hazardous Substances Data)

Usage

Medical Use

Treats various types of irregular heartbeats

Mechanism of Action

Affects electrical activity in the heart to maintain a normal rhythm

Chemical Structure

Phenol structure with chlorine and amine groups attached to the benzene ring

Classification

Class III antiarrhythmic agent

Forms

Tablets and injectables for medical administration

Research

Investigated for potential use in cancer treatment and other medical conditions

InChI:InChI=1/C8H10ClNO/c9-7-5-6(3-4-10)1-2-8(7)11/h1-2,5,11H,3-4,10H2

Upstream product

• 51-67-2 tyrosamine 
• 7423-93-0 (S)-2-amino-3-(3-chloro-4-hydroxyphenyl)propanoic acid 
• 64318-28-1 N-t-butoxycarbonyl-tyramine 

Relevant articles and documents

A process for preparing a broad pH fluorescent probe of the organic compound and use thereof (by machine translation)

The present invention discloses a process for the preparation of a wide range of fluorescent probe in the pH of the organic compound, the organic compound can be produced according to the actual need to carry out any proportion of combination, and can be fixed in the hydrophilic high polymer further preparing and detecting water environment acidity and alkalinity of the product. The product can be realized to the pH value of the continuous measuring, thereby greatly improving the efficiency, sensitivity and repeatability. (by machine translation)

Aromatic L-Amino Acid Decarboxylase from Micrococcus percitreus Purification, Crystallization and Properties

An aromatic L-amino acid decarboxylase was crystallized from the cell free extract of Micrococcus percitreus.The purification procedure included protamine sulfate treatment, ammonium sulfate fractionation, DEAE-Sephadex column chromatography and Sephadex G-200 filtration.Crystals were obtained from a solution of the purified enzyme by addition of ammonium sulfate.The crystalline enzyme preparation was homogeneous as judged by ultracentrifugation and SDS-polyacrylamide gel electrophoresis.The molecular weight was determined to be approximately 101,000.The enzyme was evidently composed of two identical subunits of a molecular weight of 48,000.The enzyme catalyzed the stoichiometric conversion of L-tryptophan to tryptamine and CO2 in the presence of pyridoxal phosphate.The optimum pH was 9.0 for the conversion.The Km value and the maximum velocity of L-tryptophan decarboxylation were 2.4E-3 M and 44 μmol/min/mg of protein, respectively.This enzyme also catalyzed decarboxylation of 5-hydroxy-L-tryptophan, L-phenylalanine, L-tyrosine, 3,4-dihydroxy-L-phenylalanine, L-kynurenine and thier α-methyl amino acid derivatives.