325735-44-2

Basic information

• Product Name: [2'R,3'S]-10-allyl-13-O-(3-tert-butoxycarbonylamino-2-O-triethylsilyl-3-phenylisoserinyl)-10-deacetoxy-7-O-triethylsilylbaccatin III
• Synonyms: [2'R,3'S]-10-allyl-13-O-(3-tert-butoxycarbonylamino-2-O-triethylsilyl-3-phenylisoserinyl)-10-deacetoxy-7-O-triethylsilylbaccatin III
• CAS NO: 325735-44-2
• Molecular Weight: 1060.48
• Mol File: 325735-44-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2'R,3'S]-10-allyl-13-O-(3-tert-butoxycarbonylamino-2-O-triethylsilyl-3-phenylisoserinyl)-10-deacetoxy-7-O-triethylsilylbaccatin III(CAS DataBase Reference)
• NIST Chemistry Reference: [2'R,3'S]-10-allyl-13-O-(3-tert-butoxycarbonylamino-2-O-triethylsilyl-3-phenylisoserinyl)-10-deacetoxy-7-O-triethylsilylbaccatin III(325735-44-2)
• EPA Substance Registry System: [2'R,3'S]-10-allyl-13-O-(3-tert-butoxycarbonylamino-2-O-triethylsilyl-3-phenylisoserinyl)-10-deacetoxy-7-O-triethylsilylbaccatin III(325735-44-2)

Safety Data

• Hazardous Substances Data: 325735-44-2(Hazardous Substances Data)

Upstream product

• 325735-33-9 [10R]-10-deacetoxy-(3-p-toluenesulfonyloxypropyl)-7-O-triethylsilylbaccatin III 
• 325735-50-0 10-deacetoxy-10-[2-(o-nitrophenylselenyl)ethyl]-7-O-triethylsilylbaccatin III 
• 325735-41-9 10-deacetoxy-10-(3-methanesulfinylpropyl)-7-O-triethylsilylbaccatin III 
• 204764-74-9 10-deacetoxy-10-hydroxypropyl-7-O-triethylsilylbaccatin III 
• 149198-47-0 tert-butyl (3R,4S)-2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate 
• 208407-16-3 10-allyl-10-deacetoxy-7-O-triethylsilylbaccatin III 

Downstream Products

• 325735-46-4 [2'R,3'S]-13-O-(3-tert-butoxycarbonylamino-2-O-triethylsilyl-3-phenylisoserinyl)-10-deacetoxy-10-formylmethyl-7-O-triethylsilylbaccatin III 

Relevant articles and documents

Synthesis and antitumor activity of non-prodrug water-soluble taxoid: 10-C-aminoalkylated docetaxel analogs

To develop non-prodrugs of taxoids possessing satisfactory stability in vivo, high water solubility and potent antitumor activity, we prepared several 10-C-sec-aminoalkylated docetaxel analogs and evaluated their cytotoxicity against mouse leukemia and hu