32578-48-6Relevant articles and documents
Silver catalyzed zinc Barbier reaction of benzylic halides in water
Bieber, Lothar W.,Storch, Elisabeth C.,Malvestiti, Ivani,Da Silva, Margarete F.
, p. 9393 - 9396 (2007/10/03)
Benzylic chlorides react in aqueous dibasic potassium phosphate under silver catalysis with aromatic aldehydes in the presence of zinc dust to give 1,2-diaryl alcohols in moderate to good yields. Dimerization to bibenzyls and reduction of the halide are important side reactions. A wide range of substituted aromatic and heteroaromatic aldehydes and of substituted benzylic chlorides can be used. Aliphatic aldehydes and ketones are unreactive. A mechanism of two SET on the metal surface is discussed.
