325844-75-5

Basic information

• Product Name: 3,5-Pyridinedicarbonitrile, 6-amino-1,2-dihydro-1-(4-methylphenyl)-4-(methylthio)-2-oxo-
• CAS NO: 325844-75-5
• Molecular Formula: C15H12N4OS
• Molecular Weight: 296.352
• Mol File: 325844-75-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3,5-Pyridinedicarbonitrile, 6-amino-1,2-dihydro-1-(4-methylphenyl)-4-(methylthio)-2-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Pyridinedicarbonitrile, 6-amino-1,2-dihydro-1-(4-methylphenyl)-4-(methylthio)-2-oxo-(325844-75-5)
• EPA Substance Registry System: 3,5-Pyridinedicarbonitrile, 6-amino-1,2-dihydro-1-(4-methylphenyl)-4-(methylthio)-2-oxo-(325844-75-5)

Safety Data

• Hazardous Substances Data: 325844-75-5(Hazardous Substances Data)

Upstream product

• 74-88-4 methyl iodide 
• 6876-54-6 2-cyano-N-(4-methylphenyl)acetamide 
• 845878-13-9 2-cyano-2-(4-oxo-[1,3]dithiolan-2-ylidene)-N-p-tolyl-acetamide 
• 5147-80-8 [Bis(methylthio)methylene]malononitrile 

Relevant articles and documents

Novel nucleoside analogues: First synthesis of pyridine-4-thioglycosides and their cytotoxic evaluation

The reaction of sodium 2,2-dicyanoethene-1,1-bis(thiolate) with 2-cyano-N-arylacetamides afforded sodium pyridine-4-thiolates, coupling of the latters with 2,3,4,6-tetra-O-acetyl-D-gluco- and D-galactopyranosyl bromides, respectively, afforded new pyridine-4-thioglycosides. Ammonolysis of the latter compounds afforded the free thioglycosides. The antitumor activities of the synthesized compounds were tested against human tumor cell lines; lung (A549), colon (HCT116), liver (HEPG2), and prostate (PC3).

Synthesis of novel derivatives of 4-methylthio-N-aryl-2-pyridone and deazapurine analogues: The reaction of ketene dithioacetals with substituted acetanilides

A new one-pot synthesis of 4-methylthio-N-aryl-2-pyridones and their deazapurine analogues by the reaction of ketene dithioacetals with substituted acetanilides have been reported.