325958-70-1

Basic information

• Product Name: {4-tert-butoxycarbonylmethyl-1-[2-(4-carbamimidoyl-benzoylamino)-3-(4-fluoro-phenyl)-propionyl]-3-oxo-piperazin-2-yl}-acetic acid methyl ester
• CAS NO: 325958-70-1
• Molecular Weight: 597.644
• Mol File: 325958-70-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {4-tert-butoxycarbonylmethyl-1-[2-(4-carbamimidoyl-benzoylamino)-3-(4-fluoro-phenyl)-propionyl]-3-oxo-piperazin-2-yl}-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {4-tert-butoxycarbonylmethyl-1-[2-(4-carbamimidoyl-benzoylamino)-3-(4-fluoro-phenyl)-propionyl]-3-oxo-piperazin-2-yl}-acetic acid methyl ester(325958-70-1)
• EPA Substance Registry System: {4-tert-butoxycarbonylmethyl-1-[2-(4-carbamimidoyl-benzoylamino)-3-(4-fluoro-phenyl)-propionyl]-3-oxo-piperazin-2-yl}-acetic acid methyl ester(325958-70-1)

Safety Data

• Hazardous Substances Data: 325958-70-1(Hazardous Substances Data)

Upstream product

• 169157-67-9 (S)-3-methoxycarbonylmethyl-2-oxopiperazine-1-acetic acid tert-butyl ester 
• 17543-58-7 2S-2-benzyloxycarbonylamino-2-(4-fluorophenylmethyl)-acetic acid 
• 340732-97-0 methyl 2-[(2S)-1-[(2S)-2-[(benzyloxycarbonyl)amino]-3-(4-fluorophenyl)propanoyl]-4-[2-(tert-butoxy)-2-oxoethyl]-3-oxopiperazinyl]acetate 

Relevant articles and documents

Novel non-peptide GPIIb/IIIa antagonists: Synthesis and biological activities of 2-[4-[2-(4-amidinobenzoylamino)-2-(substituted)acetyl]-3-(2-methoxy-2- oxoethyl)-2-oxopiperazinyl] acetic acids

To improve the in vitro and in vivo potency of our first low molecular weight GPIIb/IIIa antagonist 1 (TAK-029), a series of 2-[4-[2-(4-amidinobenzoylamino)-2-(substituted)acetyl]-3-(2-methoxy-2- oxoethyl)-2-oxopiperazinyl]acetic acids were synthesized th