32598-04-2

Basic information

• Product Name: 3-[2-(pyridin-4-yl)ethenyl]aniline
• CAS NO: 32598-04-2
• Molecular Formula: C₁₃H₁₂N₂
• Molecular Weight: 196.2478
• Mol File: 32598-04-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 388.7°C at 760 mmHg
• Flash Point: 217.3°C
• Density: 1.167g/cm³
• Vapor Pressure: 3E-06mmHg at 25°C
• Refractive Index: 1.713
• CAS DataBase Reference: 3-[2-(pyridin-4-yl)ethenyl]aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[2-(pyridin-4-yl)ethenyl]aniline(32598-04-2)
• EPA Substance Registry System: 3-[2-(pyridin-4-yl)ethenyl]aniline(32598-04-2)

Safety Data

• Hazardous Substances Data: 32598-04-2(Hazardous Substances Data)

Upstream product

• 46837-95-0 4-[2-(3-nitrophenyl)ethenyl]pyridine 
• 585-79-5 m-nitrobromobenzene 
• 100-43-6 4-vinylpyridine 
• 591-19-5 m-Bromoaniline 

Downstream Products

• 1173003-00-3 N-(3-diethylamino-propyl)-3-[3-((E)-2-pyridin-4-yl-vinyl)-phenylamino]-benzamide 
• 1173003-01-4 N-(3-methyl-butyl)-3-[3-((E)-2-pyridin-4-yl-vinyl)-phenylamino]-benzamide 
• 1401773-86-1 (E)-N-(3-diethylaminopropyl)-3-[3-(2-pyridin-4-ylvinyl)phenylamino]benzenesulfonamide 

Relevant articles and documents

Inhibitory effect of cytotoxic nitrogen-containing heterocyclic stilbene analogues on VEGF protein secretion and VEGF, hTERT and c-Myc gene expression

A group of 21 nitrogen-containing heterocyclic stilbene derivatives, prepared by means of Heck coupling reactions, has been investigated for their cytotoxicity as well as their ability to inhibit the production of the vascular endothelial growth factor (VEGF) and the activation of telomerase. The ability of these compounds to inhibit proliferation of two tumoral cell lines (HT-29 and MCF-7) and one non-tumoral cell line (HEK-293) was first determined. Subsequently, we determined the capacity of the compounds to inhibit the secretion of VEGF in the aforementioned cell lines and downregulate the expression of the VEGF, hTERT and c-Myc genes, of which the latter two are involved in controlling the activation of telomerase.

Irreversible enzyme inhibitors. 181. Inhibition of brain choline acetyltransferase by derivatives of 4-stilbazole.

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