326902-40-3

Basic information

• Product Name: PropanaMide, N-(2-iodophenyl)-2-Methyl-
• Synonyms: PropanaMide, N-(2-iodophenyl)-2-Methyl-;N-(2-iodophenyl)-2-methylpropanamide
• CAS NO: 326902-40-3
• Molecular Formula: C₁₀H₁₂INO
• Molecular Weight: 289.11285
• Mol File: 326902-40-3.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: PropanaMide, N-(2-iodophenyl)-2-Methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: PropanaMide, N-(2-iodophenyl)-2-Methyl-(326902-40-3)
• EPA Substance Registry System: PropanaMide, N-(2-iodophenyl)-2-Methyl-(326902-40-3)

Safety Data

• Hazardous Substances Data: 326902-40-3(Hazardous Substances Data)

Upstream product

• 615-43-0 2-iodophenylamine 
• 79-30-1 isobutyryl chloride 

Downstream Products

• 591219-74-8 N-(2-iodophenyl)-N-methylisobutyramide 
• 17626-86-7 2-isopropyl-benzothiazole 
• 1262501-18-7 (E)-N-(2-(3,4-dimethoxystyryl)phenyl)isobutyramide 
• 20200-86-6 1,3,3-trimethyl-1,3-dihydro-2H-indol-2-one 
• 55577-65-6 2,N-dimethyl-N-phenylpropanamide 
• 4406-41-1 N-phenylisobutyramide 
• 6797-15-5 2-isopropyl-1,3-benzoxazole 

Relevant articles and documents

Synthesis, Biological Evaluation of ortho-Carboxamidostilbenes as Potential Inhibitors of Hyperglycemic Enzymes, and Molecular Docking Study

A new series of ortho-carboxamidostilbenes derivatives were synthesized via Heck Coupling and screened for their α-amylase and α-glucosidase inhibitory potential. The results indicated that all the synthesized compounds showed a substantial α-glucosidase

Facile synthesis of 2-benzoxazoles via CuI/2,2'-bipyridine catalyzed intramolecular C–O coupling of 2-haloanilides

Development of newer methods for the synthesis of Benzoxazoles has of greater interest due to their wide range of biological activities and pharmaceutical importance. We herein report a facile and general method for the synthesis of 2-substituted Benzoxazoles via copper catalyzed intramolecular C–O cross-coupling of 2-haloanilides. A combination of CuI (5 mol%), 2,2'-bipyridine (10 mol%), Cs2CO3 (2 equiv.) in DMF solvent with 4 ? molecular sieves at 140 °C, illustrated the scope for tuning the reactivity of 2-haloanilides toward the selective formation of a series of 2-alkyl benzoxazole derivatives in moderate to good yields. This is the first systematic study using CuI/2,2'-Bipyridine as the catalytic system for the synthesis of 2-substituted Benzoxazoles. The outcome of the reaction was found to be significantly influenced by the aromatic and amide substituents of 2-haloanilides.

Intramolecular 1,5-H transfer reaction of aryl iodides through visible-light photoredox catalysis: A concise method for the synthesis of natural product scaffolds

The intramolecular 1,5-H transfer reaction of the aryl radicals generated from unactivated aryl iodides by photocatalysis is described. The features of this transformation are operational simplicity, excellent yields, mild reaction conditions, and good fu