327161-54-6Relevant articles and documents
2-alkynyl-8-aryl-9-methyladenines as novel adenosine receptor antagonists: Their synthesis and structure-activity relationships toward hepatic glucose production induced via agonism of the A2B receptor
Harada,Asano,Hoshino,Yoshikawa,Matsukura,Kabasawa,Niijima,Kotake,Watanabe,Kawata,Inoue,Horizoe,Yasuda,Minami,Nagata,Murakami,Nagaoka,Kobayashi,Tanaka,Abe
, p. 170 - 179 (2007/10/03)
Novel adenosine antagonists, 2-alkynyl-8-aryl-9-methyladenine derivatives, were synthesized as candidate hypoglycemic agents. These analogues were evaluated for inhibitory activity on N-ethylcarboxamidoadenosine (NECA)-induced glucose production in primar