32730-32-8

Basic information

• Product Name: 5-BroMoMethyltetrahydrofuran-2-one
• Synonyms: 5-(BroMoMethyl)butyrolactone;5-BroMoMethyltetrahydrofuran-2-one;5-(bromomethyl)dihydrofuran-2(3H)-one;5-(bromomethyl)dihydro-2(3H)-furanone
• CAS NO: 32730-32-8
• Molecular Formula: C₅H₇BrO₂
• Molecular Weight: 179.01188
• Mol File: 32730-32-8.mol
• Article Data: 47

Chemical Properties

• Boiling Point: 165 °C(Press: 26 Torr)
• Appearance: /
• Density: 1.619±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 5-BroMoMethyltetrahydrofuran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BroMoMethyltetrahydrofuran-2-one(32730-32-8)
• EPA Substance Registry System: 5-BroMoMethyltetrahydrofuran-2-one(32730-32-8)

Safety Data

• Hazardous Substances Data: 32730-32-8(Hazardous Substances Data)

Upstream product

• 10374-51-3 5-hydroxymethyl-4,5-dihydrofuranone 
• 591-80-0 pent-4-enoic acid 
• 848949-92-8 (S)-4-Fluoro-4-methyl-2-pent-4-enoylamino-pentanoic acid ethyl ester 
• 39716-58-0 pent-4-enoyl chloride 
• 848949-90-6 2-but-3-enyl-4-(2-fluoro-2-methyl-propyl)-4H-oxazol-5-one 
• 848949-88-2 4-fluoro-4-methyl-2-pent-4-enoylamino-pentanoic acid 
• 1180676-13-4 N-(5-bromo-methyltetrahydrofuran-2-ylidene)pyrrolidinium bromide 
• 14594-23-1 5-bromolaevulinic acid 
• 53856-93-2 methyl 5-bromo-4-oxopentanoate 

Downstream Products

• 10035-10-6 hydrogen bromide 
• 695-06-7 hexan-4-olide 

Relevant articles and documents

Synthesis of Benzoisoselenazolone Derivatives by Nickel-Catalyzed Dehydrogenative Direct Selenation of C(sp2)-H Bonds with Elemental Selenium in Air

Nickel-catalyzed direct selenation of benzamides bearing an 8-quinolyl auxiliary with elemental selenium provides benzoisoselenazolones in good yield via carbon-selenium and nitrogen-selenium bond formation under aerobic conditions. In addition to aryl C-

Bromoiodinanes with an I(III)-Br bond: Preparation, X-ray crystallography and reactivity as electrophilic brominating agents

Bromoiodinanes - conveniently and directly prepared from iodobenzenecarbinols and N-bromosuccinimide, and characterised for the first time crystallographically - act as electrophilic bromine donors. The Royal Society of Chemistry 2006.

H2O2 Production at Low Overpotentials for Electroenzymatic Halogenation Reactions

Various enzymes utilize hydrogen peroxide as an oxidant. Such “peroxizymes” are potentially very attractive catalysts for a broad range of oxidation reactions. Most peroxizymes, however, are inactivated by an excess of H2O2. The electrochemical reduction of oxygen can be used as an in situ generation method for hydrogen peroxide to drive the peroxizymes at high operational stabilities. Using conventional electrode materials, however, also necessitates significant overpotentials, thereby reducing the energy efficiency of these systems. This study concerns a method to coat a gas-diffusion electrode with oxidized carbon nanotubes (oCNTs), thereby greatly reducing the overpotential needed to perform an electroenzymatic halogenation reaction. In comparison to the unmodified electrode, with the oCNTs-modified electrode the overpotential can be reduced by approximately 100 mV at comparable product formation rates.

Oxidative oxygen-nucleophilic bromo-cyclization of alkenyl carbonyl compounds without organic wastes using alkali metal reagents in green solvent

A bromo-lactonization of alkenyl carboxylic acids and a bromo-cyclization of N-allyl amides as oxygen-nucleophilic bromo-cyclization reactions were developed via the oxidative umpolung of bromide using alkali metal bromide and inorganic oxidant to provide

Fenton chemistry for Achmatowicz rearrangement

Achmatowicz rearrangement (AchR) is a very important transformation for the synthesis of various heterocyclic building blocks and natural products. Here, the discovery of Fenton chemistry for AchR using a bifunctional catalyst (FeBr2 or CeBrsu

Electrochemical bromofunctionalization of alkenes in a flow reactor

The bromination of organic molecules has been extensively studied to date, yet there is still a demand for safe and sustainable methodologies. Hazardous reagents, selectivity, low atom economy and waste production are the most persisting problems of brominating reagents. The electrochemical oxidation of bromide to bromine is a viable strategy to reduce waste by avoiding chemical oxidants. Furthermore, thein situgeneration of reactive intermediates minimizes the risk of hazardous reagents. In this work, we investigate the electrochemical generation of bromine from hydrobromic acid in a flow electrochemical reactor. Various alkenes could be converted to their corresponding dibromides, bromohydrines, bromohydrin ethers and cyclized products in good to excellent yields.

Cooperativity within the catalyst: alkoxyamide as a catalyst for bromocyclization and bromination of (hetero)aromatics

Alkoxyamide has been reported as a catalyst for the activation ofN-bromosuccinimide to perform bromocyclization and bromination of a wide range of substrates in a lipophilic solvent, where adequate suppression of the background reactions was observed. The key feature of the active site is the alkoxy group attached to the sulfonamide moiety, which facilitates the acceptance as well as the delivery of bromonium species from the bromine source to the substrates.