3275-70-5 Usage
General Description
Cytidylyl-(5.3)-cytidylyl-(5.3)-uridine, also known as Cpu, is a chemical compound involved in RNA metabolism and the modification of ribosomal RNA. It consists of three nucleotides linked together by phosphodiester bonds, forming a triphosphate bridge between the second and third nucleotide. Cpu is a precursor to the complex tRNA modification mcm^5s^2U, which has important roles in ensuring accurate translation of the genetic code. This chemical compound is also involved in regulating gene expression and protein synthesis in cells. Additionally, Cpu has potential therapeutic applications in cancer treatment due to its role in protein synthesis and cell proliferation.
Check Digit Verification of cas no
The CAS Registry Mumber 3275-70-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,2,7 and 5 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3275-70:
(6*3)+(5*2)+(4*7)+(3*5)+(2*7)+(1*0)=85
85 % 10 = 5
So 3275-70-5 is a valid CAS Registry Number.
3275-70-5Relevant articles and documents
A nucleotide dimer synthesis without protecting groups using montmorillonite as catalyst
Joshi, Prakash C.,Aldersley, Michael F.,Zagorevskii, Dmitri V.,Ferris, James P.
, p. 536 - 566 (2012/10/08)
A synthesis has been developed providing nucleotide dimers comprising natural or unnatural nucleoside residues. A ribonucleoside 5-phosphorimidazolide is added to a nucleoside adsorbed on montmorillonite at neutral pH with the absence of protecting groups. Approximately 30% of the imidazolide is converted into each 2-5 dimer and 3-5 dimer with the rest hydrolyzed to the 5-monophosphate. Experiments with many combinations have suggested the limits to which this method may be applied, including heterochiral and chimeric syntheses. This greener chemistry has enabled the synthesis of dimers from activated nucleotides themselves, activated nucleotides with nucleosides, and activated nucleotides with nucleotide 5-monophosphates.