32754-06-6 Usage
Chemical structure
A nucleoside analog derivative of cytarabine, consisting of a 1-beta-D-arabinofuranosyl group attached to a 4-thioxo-3,4-dihydropyrimidin-2(1H)-one moiety.
Antineoplastic activity
Exhibits potential antineoplastic (anti-cancer) properties.
Mechanism of action
Inhibits the synthesis of DNA, RNA, and protein in cancer cells, leading to their destruction.
DNA incorporation
Can be incorporated into the DNA of cancer cells, causing DNA damage and eventual cell death.
Target diseases
Used in the treatment of various forms of leukemia and lymphoma.
Development status
Has sparked interest in its further development as a potential anticancer agent.
Check Digit Verification of cas no
The CAS Registry Mumber 32754-06-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,7,5 and 4 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 32754-06:
(7*3)+(6*2)+(5*7)+(4*5)+(3*4)+(2*0)+(1*6)=106
106 % 10 = 6
So 32754-06-6 is a valid CAS Registry Number.
32754-06-6Relevant articles and documents
Growth inhibition of Mycobacterium bovis, Mycobacterium tuberculosis and Mycobacterium avium in vitro: Effect of 1-β-D-2′-arabinofuranosyl and 1-(2′-deoxy-2′-fluoro-β-D-2′-ribofuranosyl) pyrimidine nucleoside analogs
Johar, Monika,Manning, Tracey,Tse, Christopher,Desroches, Nancy,Agrawal,Kunimoto, Dennis Y.,Kumar, Rakesh
, p. 3696 - 3705 (2008/02/09)
The resurgence of tuberculosis and the emergence of multiple-drug-resistant strains of Mycobacteria necessitate the search for new classes of antimycobacterial agents. We synthesized a series of 1-β-D-2′- arabinofuranosyl and 1-(2′-deoxy-2′-fluoro-β-D-rib
