327596-87-2

Basic information

• Product Name: N,N,N',N'-tetraisopropyl-O-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethyl] phosphordiamidite
• Synonyms: N,N,N',N'-tetraisopropyl-O-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethyl] phosphordiamidite
• CAS NO: 327596-87-2
• Molecular Weight: 467.632
• Mol File: 327596-87-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N,N,N',N'-tetraisopropyl-O-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethyl] phosphordiamidite(CAS DataBase Reference)
• NIST Chemistry Reference: N,N,N',N'-tetraisopropyl-O-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethyl] phosphordiamidite(327596-87-2)
• EPA Substance Registry System: N,N,N',N'-tetraisopropyl-O-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethyl] phosphordiamidite(327596-87-2)

Safety Data

• Hazardous Substances Data: 327596-87-2(Hazardous Substances Data)

Upstream product

• 291299-78-0 N-(2-hydroxyethyl)-N-isopropyl-4-methoxybenzamide 
• 100-07-2 4-methoxy-benzoyl chloride 
• 109-56-8 i-propyl(2-(hydroxy)ethyl)amine 
• 56183-63-2 bis(diisopropylamino)chlorophosphine 

Downstream Products

• 291299-91-7 N⁶-benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-(N,N-diisopropylamino)-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethoxy]phosphinyl-2'-deoxyadenosine 
• 291299-92-8 N⁴-benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-(N,N-diisopropylamino)-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethoxy]phosphinyl-2'-deoxycytidine 
• 291299-79-1 5'-O-(4,4'-dimethoxytrityl)-3'-O-(N,N-diisopropylamino)-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethoxy]phosphinyl-2'-deoxythymidine 

Relevant articles and documents

Novel phosphate and thiophosphate protecting groups

Novel P(III) bisamidite reagents as phosphorus protecting groups, nucleoside phosphoramidite intermediates, and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared through the protection of one or more int

A novel protecting strategy for internucleosidic phosphate and phosphorothioate groups

The utility of 2-(N-isopropyl-N-anisoylamino)ethyl group for protection of intemucleosidic phosphate linkages in oligonucleotide synthesis was studied. The group demonstrated high coupling yields, favorable deprotection kinetics and a high hydrolytic stability of phosphoramidite building blocks. The mechanism of deprotection was established using a model phosphate triester.