327600-47-5

Basic information

• Product Name: Carbamic acid, [(1R)-1-acetyl-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, [(1R)-1-acetyl-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)
• CAS NO: 327600-47-5
• Molecular Formula: C11H21NO3
• Molecular Weight: 215.28934
• Product Categories: N-BOC
• Mol File: 327600-47-5.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Carbamic acid, [(1R)-1-acetyl-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1R)-1-acetyl-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)(327600-47-5)
• EPA Substance Registry System: Carbamic acid, [(1R)-1-acetyl-2-methylpropyl]-, 1,1-dimethylethyl ester (9CI)(327600-47-5)

Safety Data

• Hazardous Substances Data: 327600-47-5(Hazardous Substances Data)

Upstream product

• 75-16-1 methylmagnesium bromide 
• 58561-04-9 N-tert-butoxycarbonyl-L-valine methyl ester 
• 13734-41-3 t-Boc-L-valine 

Downstream Products

• 265996-24-5 (4S)-5-ethenyl-4-(2-propyl)-5-methyloxazolidin-2-one 
• 1277097-39-8 tert-butyl (S)-4-methyl-2-oxopentan-3-ylcarbamate 
• 35150-08-4 Boc-Val-NH₂ 
• 70717-76-9 (R)-(1-carbamoyl-2-methyl-propyl)-carbamicacidtert-butyl ester 
• 473732-43-3 C₁₃H₂₀N₂O*ClH 

Relevant articles and documents

2-AMINOPYRIMIDINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF

The disclosure provides an aminopyrimidine derivative for preventing and treating diseases related to IDH mutation, a preparation method and use thereof. Specifically, the disclosure provides a compound of Formula I, a stereoisomer, racemate thereof, or pharmaceutically acceptable salt thereof. The compound of the general Formula I has isocitrate dehydrogenase 1 (IDH1) inhibitory activity and can treat cancer induced by IDH1 mutation.

Access to enantiomerically enriched cis-2,3-disubstituted azetidines via diastereoselective hydrozirconation

An asymmetric variant of the hydrozirconation reaction has been established starting from Boc-protected chiral allylic amines. The resulting diastereoselectively formed N-functionalized organozirconiums can be considered as promising chirons. In this case

A practical procedure for the multigram synthesis of the SuperQuat chiral auxiliaries

An efficient and simple synthesis of oxazolidin-2-one SuperQuat chiral auxiliaries is described which provides rapid access to multigram quantities of the auxiliaries.