32778-16-8

Basic information

• Product Name: 2,2-difluoroethyl difluoromethyl ether
• Synonyms: 2-(Difluoromethoxy)-1,1-difluoroethane; 2,2-Difluoroethyl difluoromethyl ether; ethane, 2-(difluoromethoxy)-1,1-difluoro-
• CAS NO: 32778-16-8
• Molecular Formula: C₃H₄F₄O
• Molecular Weight: 132.0569
• Mol File: 32778-16-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 32.8°C at 760 mmHg
• Density: 1.234g/cm³
• Vapor Pressure: 574mmHg at 25°C
• Refractive Index: 1.271
• CAS DataBase Reference: 2,2-difluoroethyl difluoromethyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-difluoroethyl difluoromethyl ether(32778-16-8)
• EPA Substance Registry System: 2,2-difluoroethyl difluoromethyl ether(32778-16-8)

Safety Data

• Hazardous Substances Data: 32778-16-8(Hazardous Substances Data)

Upstream product

• 75-45-6 Chlorodifluoromethane 
• 359-13-7 difluoroethanol 

Relevant articles and documents

Reactions of aliphatic fluoro-alcohols with CHClF2 at atmospheric pressure

The reactions of aliphatic fluoro-alcohols with chlorodifluoromethane (CHClF2) at atmospheric pressure were examined. In the reaction of CF3CF2CH2OH, the difluoromethylated ether was obtained in moderate yield by using ethers such as 1,4-dioxane, diglyme and THF, or their mixtures with water as a reaction solvent. While acetal and orthoformate were also produced, the selectivity of the difluoromethylated ether could be improved by adding water to the reaction. The effect of water could be explained by the reaction mechanism.