328-87-0 Usage
Description
2-CHLORO-5-(TRIFLUOROMETHYL)BENZONITRILE is a white to light yellow crystal powder that is synthesized through the Sandmeyer reaction of 2-chloro-5-trifluoromethylaniline with copper cyanide/sodium cyanide. It is a chemical compound with potential applications in various industries.
Uses
Used in Water Supply Systems:
2-CHLORO-5-(TRIFLUOROMETHYL)BENZONITRILE is used as a component in the production of a thermal coupler control system for water supply systems. This application helps regulate the temperature and flow of water, ensuring efficient and effective water management.
Used in Chemical Synthesis:
As a chemical compound, 2-CHLORO-5-(TRIFLUOROMETHYL)BENZONITRILE can be utilized in the synthesis of various other chemicals and materials. Its unique properties make it a valuable intermediate in the production of different compounds, contributing to the development of new products and technologies.
Used in Pharmaceutical Industry:
2-CHLORO-5-(TRIFLUOROMETHYL)BENZONITRILE may also find applications in the pharmaceutical industry, where it can be used as a building block for the development of new drugs or as a reagent in the synthesis of existing medications. Its specific chemical properties make it a promising candidate for further research and development in this field.
Used in Research and Development:
Due to its unique chemical structure, 2-CHLORO-5-(TRIFLUOROMETHYL)BENZONITRILE can be employed in research and development activities, particularly in the fields of organic chemistry and materials science. It can be used to study various chemical reactions and properties, leading to a better understanding of its potential applications and benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 328-87-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,2 and 8 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 328-87:
(5*3)+(4*2)+(3*8)+(2*8)+(1*7)=70
70 % 10 = 0
So 328-87-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H3ClF3N/c9-7-2-1-6(8(10,11)12)3-5(7)4-13/h1-3H
328-87-0Relevant articles and documents
Scale-up and safety evaluation of a sandmeyer reaction
Nielsen, Martin Anker,Nielsen, Michael Kim,Pittelkow, Thomas
, p. 1059 - 1064 (2004)
A scale-up of a new process for the production of 2-chloro-5- trifluoromethyl-benzonitrile by a Sandmeyer reaction of 2-Chloro-5- trifluoromethylaniline with copper cyanide/sodium cyanide is described. To ensure a safe implementation, a safety evaluation of the process was carried out, which is described in the following. The new process gives a better working environment and better productivity due to shorter reaction time.
Synthesis of nitriles from amines using nanoscale Co3O4-based catalysts via sustainable aerobic oxidation
Natte, Kishore,Jagadeesh, Rajenahally V.,Sharif, Muhammad,Neumann, Helfried,Beller, Matthias
supporting information, p. 3356 - 3359 (2016/04/09)
The selective oxidation of amines for the benign synthesis of nitriles under mild conditions is described. Key to success for this transformation is the application of reusable cobalt oxide-based nanocatalysts. The resulting nitriles constitute key precursors and central intermediates in organic synthesis.
Process for producing trifluoromethylbenzylamines
-
, (2008/06/13)
The invention relates to a process for producing a trifluotomethylbenzylamine represented by the following general formula (1), 1where each R independently represents a halogen selected from the group consisting of fluorine, chlorine, bromine and iodine, an alkyl group having a carbon atom number of 1-4, an alkoxy group having a carbon atom number of 1-4, an amino group, a hydroxyl group or a trifluoromethyl group, and n represents an integer from 0 to 4. The process includes hydrogenating a trifluoromethylbenzonitrile by hydrogen in an organic solvent in the presence of ammonia and a catalyst containing a platinum group element. This trifluoromethylbenzonitrile is represented by the following general formula (2), 2where R and n are defined as above. With this process, it is possible to obtain the trifluoromethylbenzylamine at an extremely high yield.
