328040-21-7Relevant articles and documents
Novel and potent anti-malarial agents
Brinner, Kristin M,Mi Kim, Jin,Habashita, Hiromu,Gluzman, Ilya Y,Goldberg, Daniel E,Ellman, Jonathan A
, p. 3649 - 3661 (2007/10/03)
Readily accessible, novel, and potent anti-malarial compounds have been developed. Optimization of the initial lead structure resulted in derivatives with IC50 values from 7 to 35 nM against chloroquine-sensitive and 70-350 nM against chloroquine-resistant strains of Plasmodium falciparum.