328045-73-4

Basic information

• Product Name: 2-(broMoMethyl)-1-Methyl-1H-indole-3-carbonitrile
• Synonyms: 2-(broMoMethyl)-1-Methyl-1H-indole-3-carbonitrile
• CAS NO: 328045-73-4
• Molecular Formula: C₁₁H₉BrN₂
• Molecular Weight: 249.10656
• Mol File: 328045-73-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 159.0-160.3 °C
• Boiling Point: 392.0±27.0 °C(Predicted)
• Appearance: /
• Density: 1.44±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2-(broMoMethyl)-1-Methyl-1H-indole-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(broMoMethyl)-1-Methyl-1H-indole-3-carbonitrile(328045-73-4)
• EPA Substance Registry System: 2-(broMoMethyl)-1-Methyl-1H-indole-3-carbonitrile(328045-73-4)

Safety Data

• Hazardous Substances Data: 328045-73-4(Hazardous Substances Data)

Upstream product

• 51072-84-5 1,2-dimethyl-1H-indole-3-carbonitrile 
• 51072-83-4 2-methyl-1H-indole-3-carbonitrile 

Downstream Products

• 938326-96-6 2-benzyl-1-methyl-1H-indole-3-carbonitrile 

Relevant articles and documents

Copper-catalyzed benzylic C-H oxygenation under an oxygen atmosphere via N-H imines as an intramolecular directing group

Copper-catalyzed benzylic C-H oxygenation under an oxygen atmosphere was developed starting from carbonitriles and Grignard reagents via N-H imine intermediates. The present process is characterized by the following two-step sequence in a one-pot manner: (1) addition of Grignard reagents to carbonitriles to form N-H imines and (2) benzylic C-H oxygenation (C=O bond formation) triggered by 1,5-hydrogen atom transfer with transient iminyl copper species.