328405-10-3

Basic information

• Product Name: (S)-ethyl 1-(1-azido-2-{[(benzyloxy)carbonyl]amino}ethyl)cyclopropanecarboxylate
• Synonyms: (S)-ethyl 1-(1-azido-2-{[(benzyloxy)carbonyl]amino}ethyl)cyclopropanecarboxylate
• CAS NO: 328405-10-3
• Molecular Weight: 332.359
• Mol File: 328405-10-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-ethyl 1-(1-azido-2-{[(benzyloxy)carbonyl]amino}ethyl)cyclopropanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-ethyl 1-(1-azido-2-{[(benzyloxy)carbonyl]amino}ethyl)cyclopropanecarboxylate(328405-10-3)
• EPA Substance Registry System: (S)-ethyl 1-(1-azido-2-{[(benzyloxy)carbonyl]amino}ethyl)cyclopropanecarboxylate(328405-10-3)

Safety Data

• Hazardous Substances Data: 328405-10-3(Hazardous Substances Data)

Upstream product

• 328405-08-9 ethyl 1-[2-(benzyloxycarbonylamino)-1-hydroxyethyl]-cyclopropanecarboxylate 
• 1279116-77-6 ethyl 1-(2-azidoacetyl)cyclopropanecarboxylate 
• 220969-66-4 ethyl 1-[2-(benzyloxycarbonylamino)acetyl]-cyclopropanecarboxylate 
• 32933-03-2 ethyl 1-acetylcyclopropanecarboxylate 
• 141-97-9 ethyl acetoacetate 
• 129306-05-4 ethyl 1-(2-bromoacetyl)cyclopropanecarboxylate 

Downstream Products

• 903900-37-8 (S)-7-amino-5-azaspiro[2.4]heptan-4-one 

Relevant articles and documents

Synthesis of (S)-7-amino-5-azaspiro[2.4]heptane via highly enantioselective hydrogenation of protected ethyl 1-(2-aminoaceto)cyclopropanecarboxylates

Highly effective asymmetric hydrogenation of protected ethyl 1-(2-aminoaceto)cyclopropane carboxylates in the presence of [RuCl(benzene)(S)-SunPhos]Cl was realized, and high enantioselectivities (up to 98.7% ee) were obtained. This asymmetric hydrogenation provides a key intermediate for the enantioselective synthesis of (S)-7-amino-5-azaspiro[2.4] heptane moiety of quinolone antibacterial agents.