3289-82-5

Basic information

• Product Name: 1H-Indole, 1-hydroxy-
• CAS NO: 3289-82-5
• Molecular Formula: C8H7NO
• Molecular Weight: 133.15
• Mol File: 3289-82-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 1-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 1-hydroxy-(3289-82-5)
• EPA Substance Registry System: 1H-Indole, 1-hydroxy-(3289-82-5)

Safety Data

• Hazardous Substances Data: 3289-82-5(Hazardous Substances Data)

Usage

Chemical Family

1H-Indole, 1-hydroxybelongs to the indole family of chemical compounds.

Derivative

1H-Indole, 1-hydroxyis a derivative of indole and is commonly found in the human body as a metabolic product of tryptophan, an essential amino acid.

Pharmaceutical Synthesis

1H-Indole, 1-hydroxyis often used as a precursor in the synthesis of various pharmaceutical drugs.

Kidney Function Measurement

1H-Indole, 1-hydroxyis known for its role in the measurement of kidney function through the detection of indoxyl sulfate in urine.

Indigo Dyes

1H-Indole, 1-hydroxyis a key intermediate in the production of indigo dyes.

Organic Synthesis and Chemical Research

1H-Indole, 1-hydroxyhas applications in the field of organic synthesis and chemical research.

Upstream product

• 120-72-9 indole 
• 1969-73-9 (2-nitrophenyl)acetaldehyde 

Downstream Products

• 120-72-9 indole 
• 144219-59-0 α,α-diphenyl-1-(methoxymethoxy)indole-2-methanol 
• 144219-57-8 α-methyl-α-phenyl-1-(methoxymethoxy)indole-2-methanol 
• 144219-60-3 1-(1H-indol-2-yl)-1-phenylethan-1-ol 
• 144219-61-4 2-(1-phenylethyl)-1h-indole 
• 47223-94-9 2-diphenylmethyl-1H-indole 
• 20538-21-0 α,α-diphenylindole-2-methanol 
• 19005-93-7 1H-indol-2-ylcarboxaldehyde 
• 68156-97-8 (+/-)-6,7-seco-agroclavine 
• 67282-55-7 1-methoxy-1H-indole-3-carbaldehyde 
• 79844-33-0 2-(2-nitrophenyl)acetaldehyde dimethyl acetal 
• 1969-73-9 (2-nitrophenyl)acetaldehyde 
• 91913-76-7 1-methoxyindole-3-carboxylic acid 
• 30536-48-2 (1-methoxy-1H-indol-3-yl)acetonitrile 

Relevant articles and documents

Ultrathin Amorphous/Crystalline Heterophase Rh and Rh Alloy Nanosheets as Tandem Catalysts for Direct Indole Synthesis

Heterogeneous noble-metal-based catalysis plays an essential role in the production of fine chemicals. Rh-based catalysts are one of the most active candidates for indole synthesis. However, it is still highly desired to develop heterogeneous Rh-based catalysts with high activity and selectivity. In this work, a general, facile wet-chemical method is reported to synthesize ultrathin amorphous/crystalline heterophase Rh and Rh-based bimetallic alloy nanosheets (NSs), including RhCu, RhZn, and RhRu. Impressively, the amorphous/crystalline heterophase Rh NSs exhibit enhanced catalytic activity toward the direct synthesis of indole compared to the crystalline counterpart. Importantly, the obtained amorphous/crystalline heterophase RhCu alloy NSs can further enhance the selectivity to indole of >99.9% and the conversion is 100%. This work demonstrates the importance of phase engineering and metal alloying in the rational design and synthesis of tandem heterogeneous catalysts toward fine chemical synthesis.

Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor

Disclosed are novel compounds having the formula or a physiologically acceptable salt, amide, ester or prodrug thereof. The compounds can be used to modulate (antagonize, agonize) chemokine receptor function. Also disclosed is a method for treating a patient having an inflammatory disease and/or viral infection comprising administering an effective amount of a compound of Formula I. In particular embodiments, the invention is a method for treating a patient infected with HIV.