32892-18-5Relevant articles and documents
Polysubstituted ethylene compound as well as preparation method and application thereof
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Paragraph 0125-0129; 0230-0234, (2020/12/30)
The invention discloses a polysubstituted ethylene compound as well as a preparation method and application thereof. The invention particularly discloses a preparation method of a polysubstituted ethylene compound as shown in a formula III, which comprises the following step: in an organic solvent, carrying out reaction as shown in the specification on a compound as shown in a formula I and a compound as shown in a formula II in the presence of a palladium catalyst, a phosphine ligand and alkali to obtain the polysubstituted ethylene compound as shown in the formula III. The preparation methodcan be suitable for various types of substrates, and the configuration of double bonds is controllable.
Following palladium catalyzed methoxycarbonylation by hyperpolarized NMR spectroscopy: A: para hydrogen based investigation
Guan, Dexin,Jonathan Holmes,López-Serrano, Joaquín,Duckett, Simon B.
, p. 2101 - 2109 (2017/07/15)
Pd(OTf)2(bcope) is shown to react in methanol solution with diphenylacetylene, carbon monoxide and hydrogen to produce the methoxy-carbonylation product methyl 2,3 diphenyl acrylate alongside cis- and trans-stilbene. In situ NMR studies harnessing the parahydrogen induced polarization effect reveal substantially enhanced 1H NMR signals in both protic and aprotic solvents for a series of reaction intermediates that play a direct role in this homogeneous transformation. Exchange spectroscopy (EXSY) measurements reveal that the corresponding CO adducts are less reactive than their methanol counterparts.
The non-metathetic role of Grubbs' carbene complexes: From hydrogen-free reduction of α,β-unsaturated alkenes to solid-supported sequential cross-metathesis/reduction
Poeylaut-Palena, Andres A.,Testero, Sebastian A.,Mata, Ernesto G.
supporting information; experimental part, p. 1565 - 1567 (2011/03/20)
An efficient and high-yielding "hydrogen-free" reduction of α,β-unsaturated alkenes was carried out employing Grubbs' catalyst in a non-metathetic role and Et3SiH. Conditions were optimized under microwave irradiation. Application to the solid-phase organic synthesis allows a facile construction of sp3-sp3 carbon bonds through a sequential cross metathesis/olefin reduction.