32894-08-9

Basic information

• Product Name: benzyl dithioacetate
• Synonyms: benzyl dithioacetate
• CAS NO: 32894-08-9
• Molecular Weight: 182.31
• Mol File: 32894-08-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: benzyl dithioacetate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl dithioacetate(32894-08-9)
• EPA Substance Registry System: benzyl dithioacetate(32894-08-9)

Safety Data

• Hazardous Substances Data: 32894-08-9(Hazardous Substances Data)

Upstream product

• 32362-99-5 benzylthioacetate 
• 594-03-6 dithioacetic acid 
• 100-51-6 benzyl alcohol 
• 75-15-0 carbon disulfide 
• 100-39-0 benzyl bromide 
• 2344-80-1 Chloromethyltrimethylsilane 
• 676-58-4 methylmagnesium chloride 
• 100-53-8 phenylmethanethiol 
• 64-19-7 acetic acid 
• 100555-97-3 bis (benzylthio)-2,4 dithio-2,4 dithiadiphosphetane-1,3,2,4 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 120060-18-6 5-Benzylthio-3H-1,2-dithiole-3-thione 
• 137021-75-1 (3E)-4-benzylthio-4-methylthiobut-3-en-2-ol 
• 137021-74-0 (3Z)-4-benzylthio-4-methylthiobut-3-en-2-ol 
• 147878-13-5 1-{4-Phenyl-5-[1-phenyl-meth-(Z)-ylidene]-4,5-dihydro-[1,3,4]thiadiazol-2-yl}-ethanone 
• 137021-73-9 3-hydroxybutanedithioate de benzyle 

Relevant articles and documents

Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same

Disclosed herein are embodiments of a donor compound that releases H2S by reacting with a reactive compound. The donor compound embodiments described herein can be used to deliver H2S to a subject or a sample and further can be used to administer therapeutic agents. The donor compound embodiments also can facilitate bioconjugation. Methods of making and using the donor compound embodiments also are disclosed.

Thiocarbonylthio compounds (S=C(Z)S-R) in free radical polymerization with reversible addition-fragmentation chain transfer (RAFT polymerization). Effect of the activating Group Z

Free-radical polymerization in the presence of suitable addition-fragmentation chain transfer agents [S=C(Z)S-R] (RAFT agents) possess the characteristics of a living polymerization (i.e., polymer products can be reactivated for chain extension and/or block synthesis, molecular weights are predetermined by RAFT agent concentration and conversion, narrow polydispersities are possible). Styrene polymerizations (110°C, thermal initiation) were performed for two series of RAFT agents [S=C(Z)S-CH2Ph and S=C(Z)S-C(Me)2CN]. The chain transfer coefficients decrease in the series where Z is Ph > SCH2Ph ～ SMe ～ Me ～ N-pyrrolo ? OC6F5 > N-lactam > OC6H5 > O(alkyl) ? N(alkyl)2 (only the first five in this series provide narrow polydispersity polystyrene ( trithiocarbonates ～ dithioalkanoates > dithiocarbonates (xanthates) > dithiocarbamates. However, electron-withdrawing substituents on Z can enhance the activity of RAFT agents to modify the above order. Thus, substituents that render the oxygen or nitrogen lone pair less available for delocalization with the C=S can substantially enhance the effectiveness of xanthates or dithiocarbamates, respectively. The trend in relative effectiveness of the RAFT agents is rationalized in terms of interaction of Z with the C=S double bond to activate or deactivate that group toward free radical addition. Molecular orbital calculations and the estimated LUMO energies of the RAFT agents can be used in a qualitative manner to predict the effect of the Z substituent on the activity of RAFT agents.

Synthesis of Dithioic Acid Esters by a Mitsunobu-Type Reaction of Alkanedithioic Acids and Alcohols

Alcohols react with dithioic acids in the presence of the complex of diisopropyl azodicarboxylate and triphenylphosphine to give various dithioic acid esters, via a Mitsunobu-type reaction.