329-63-5 Usage
Description
DL-Adrenaline Hydrochloride, also known as (±)-Epinephrine Hydrochloride, is a synthetic compound that acts as an adrenergic receptor agonist. It is a bronchodilator and has various applications in different industries due to its ability to stimulate the adrenergic receptors.
Uses
Used in Pharmaceutical Industry:
DL-Adrenaline Hydrochloride is used as a bronchodilator for the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It helps to relax the smooth muscles in the airways, allowing for easier breathing.
Used in Medical Research:
DL-Adrenaline Hydrochloride is used as an adrenergic receptor agonist in various research studies. It is used in the induction of renalase expression in human renal proximal tubular epithelial cells, which can help in understanding the role of renalase in kidney function and its potential therapeutic applications.
Used in Physiological Studies:
DL-Adrenaline Hydrochloride is used in infusion studies to test its effect on heart rate and eye temperature measurements in bulls. This helps researchers understand the physiological responses to adrenergic stimulation and its potential applications in veterinary medicine.
Used in Regenerative Medicine:
DL-Adrenaline Hydrochloride is used as a medium supplement for the stimulation of endothelial progenitor cells. This promotes the growth and differentiation of these cells, which are important for blood vessel formation and repair, and can have potential applications in tissue regeneration and wound healing.
Biochem/physiol Actions
Epinephrine improves systemic pressure during cardiopulmonary resuscitation and is used post cardiac arrest. The levels of epinephrine increases during trauma, sepsis and hypoglycemia resulting in increased cardiac rate and contractility. It is used in the treatment of acute anaphylaxis. Use of epinephrine hydrochloride enables dilation of pupil during intraocular lens (IOL) implantation surgery.
Check Digit Verification of cas no
The CAS Registry Mumber 329-63-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,2 and 9 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 329-63:
(5*3)+(4*2)+(3*9)+(2*6)+(1*3)=65
65 % 10 = 5
So 329-63-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H13NO3.2ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;;/h2-4,9-13H,5H2,1H3;2*1H/p-1/t9-;;/m0../s1
329-63-5Relevant articles and documents
A new and efficient route for the synthesis of naturally occurring catecholamines
Bernini, Roberta,Crisante, Fernanda,Barontini, Maurizio,Fabrizi, Giancarlo
experimental part, p. 3838 - 3842 (2010/03/30)
Catecholamines, sympathomimetic drugs and adrenergic receptor antagonists, have been prepared by a regioselective oxidation of the corresponding 4-hydroxyphenethylamine derivatives by 2-iodoxybenzoic acid (IBX) in homogeneous as well as in heterogeneous conditions and followed by cleavage of the amino protective group. By using polymer-supported IBX, after the first oxidation, the oxidant can be recovered, regenerated, and efficiently reused for several additional times. An efficient, easy and green procedure for the synthesis of N-(methoxycarbonyl)dopamine, key component of many pharmaceuticals, has also been reported. Georg Thieme Verlag Stuttgart.
