329041-38-5

Basic information

• Product Name: (2R,3R)-1-(4-Benzyloxy-benzenesulfonyl)-2-methyl-3-(4-methyl-2,6,7-trioxa-bicyclo[2.2.2]oct-1-yl)-aziridine
• CAS NO: 329041-38-5
• Molecular Weight: 431.51
• Mol File: 329041-38-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R)-1-(4-Benzyloxy-benzenesulfonyl)-2-methyl-3-(4-methyl-2,6,7-trioxa-bicyclo[2.2.2]oct-1-yl)-aziridine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-1-(4-Benzyloxy-benzenesulfonyl)-2-methyl-3-(4-methyl-2,6,7-trioxa-bicyclo[2.2.2]oct-1-yl)-aziridine(329041-38-5)
• EPA Substance Registry System: (2R,3R)-1-(4-Benzyloxy-benzenesulfonyl)-2-methyl-3-(4-methyl-2,6,7-trioxa-bicyclo[2.2.2]oct-1-yl)-aziridine(329041-38-5)

Safety Data

• Hazardous Substances Data: 329041-38-5(Hazardous Substances Data)

Upstream product

• 329041-35-2 [(1R,2S)-2-Hydroxy-1-(4-methyl-2,6,7-trioxa-bicyclo[2.2.2]oct-1-yl)-propyl]-carbamic acid benzyl ester 
• 329041-34-1 (2R,3S)-2-Benzyloxycarbonylamino-3-hydroxy-butyric acid 3-methyl-oxetan-3-ylmethyl ester 
• 329041-36-3 (1R,2S)-1-Amino-1-(4-methyl-2,6,7-trioxa-bicyclo[2.2.2]oct-1-yl)-propan-2-ol 
• 78385-26-9 3-bromomethyl-3-methyloxetane 
• 329041-37-4 4-Benzyloxy-N-[(1R,2S)-2-hydroxy-1-(4-methyl-2,6,7-trioxa-bicyclo[2.2.2]oct-1-yl)-propyl]-benzenesulfonamide 

Downstream Products

• 683211-04-3 (2R,3S)-1-(4-Benzyloxy-benzenesulfonyl)-3-methyl-2-(4-methyl-2,6,7-trioxa-bicyclo[2.2.2]oct-1-yl)-piperazine 
• 683213-42-5 (2R,3S)-1-(4-Benzyloxy-benzenesulfonyl)-3-methyl-piperazine-2-carboxylic acid allyloxy-amide 
• 683211-85-0 (2R,3S)-1-(4-Benzyloxy-benzenesulfonyl)-3-methyl-piperazine-2-carboxylic acid 

Relevant articles and documents

Synthesis and biological activity of piperazine-Based dual MMP-13 and TNF-α converting enzyme inhibitors

A series of novel MMP-13 and TNF-α converting enzyme inhibitors based on piperazine 2-hydroxamic acid scaffolds are described. The TACE, MMP-1 and MMP-13 activity of these inhibitors as well as the effect of substitution of the piperazine nitrogen and the P-1′ benzyloxy tailpiece is discussed. Moderate in vivo activity is observed with several members of this group.