32932-19-7

Basic information

• Product Name: C₁₄H₁₁NO₂
• Synonyms: C₁₄H₁₁NO₂
• CAS NO: 32932-19-7
• Molecular Weight: 225.247
• Mol File: 32932-19-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₁NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₁NO₂(32932-19-7)
• EPA Substance Registry System: C₁₄H₁₁NO₂(32932-19-7)

Safety Data

• Hazardous Substances Data: 32932-19-7(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 14268-66-7 benzo[1,3]dioxolo-5-ylamine 
• 100-51-6 benzyl alcohol 

Downstream Products

• 57489-86-8 6,7-(methylenedioxy)-2-phenylquinoline 
• 14268-66-7 benzo[1,3]dioxolo-5-ylamine 
• 32932-20-0 N-(3,4-methylendioxyphenyl)-N-benzylamine 
• 135574-99-1 [(6-Benzylamino-benzo[1,3]dioxol-5-yl)-(3,4,5-trimethoxy-phenyl)-methyl]-carbamic acid ethyl ester 
• 161616-63-3 (6-Benzylamino-benzo[1,3]dioxol-5-yl)-(3,4,5-trimethoxy-phenyl)-methanol 

Relevant articles and documents

Pt-Sn/γ-Al2O3-catalyzed highly efficient direct synthesis of secondary and tertiary amines and imines

Versatile syntheses of secondary and tertiary amines by highly efficient direct N-alkylation of primary and secondary amines with alcohols or by deaminative self-coupling of primary amines have been successfully realized by means of a heterogeneous bimetallic Pt-Sn/γ-Al2O3 catalyst (0.5 wt % Pt, Pt/Sn molar ratio=1:3) through a borrowing-hydrogen strategy. In the presence of oxygen, imines were also efficiently prepared from the tandem reactions of amines with alcohols or between two primary amines. The proposed mechanism reveals that an alcohol or amine substrate is initially dehydrogenated to an aldehyde/ketone or NH-imine with concomitant formation of a [PtSn] hydride. Condensation of the aldehyde/ketone species or deamination of the NH-imine intermediate with another molecule of amine forms an N-substituted imine which is then reduced to a new amine product by the in-situ generated [PtSn] hydride under a nitrogen atmosphere or remains unchanged as the final product under an oxygen atmosphere. The Pt-Sn/γ-Al2O 3 catalyst can be easily recycled without Pt metal leaching and has exhibited very high catalytic activity toward a wide range of amine and alcohol substrates, which suggests potential for application in the direct production of secondary and tertiary amines and N-substituted imines.

In vitro antifungal activity of new series of homoallylamines and related compounds with inhibitory properties of the synthesis of fungal cell wall polymers

The synthesis, in vitro antifungal evaluation and SAR studies of 101 compounds of the 4-aryl-, 4-alkyl-, 4-pyridyl or -quinolinyl-4-N-arylamino-1-butenes series and related compounds, are reported here. Active structures showed to inhibit (1,3)-β-D-glucan and mainly chitin synthases, enzymes that catalyze the synthesis of the major fungal cell wall polymers.