32970-32-4

Basic information

• Product Name: 5-Acetyl-6-amino-1,3-dimethyluracil
• Synonyms: 5-Acetyl-6-amino-1,3-dimethyluracil;5-Acetyl-6-amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione;5-Acetyl-6-amino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione;5-acetyl-6-amino-1,3-dimethyl-pyrimidine-2,4-dione;5-acetyl-6-amino-1,3-dimethylpyrimidine-2,4-dione;5-acetyl-6-amino-1,3-dimethyl-pyrimidine-2,4-quinone;6-amino-5-ethanoyl-1,3-dimethyl-pyrimidine-2,4-dione;MLS000089916
• CAS NO: 32970-32-4
• Molecular Formula: C8H11N3O3
• Molecular Weight: 197.19124
• Mol File: 32970-32-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 308.9°Cat760mmHg
• Flash Point: 140.6°C
• Appearance: /
• Density: 1.317g/cm³
• Vapor Pressure: 0.00066mmHg at 25°C
• Refractive Index: 1.549
• CAS DataBase Reference: 5-Acetyl-6-amino-1,3-dimethyluracil(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Acetyl-6-amino-1,3-dimethyluracil(32970-32-4)
• EPA Substance Registry System: 5-Acetyl-6-amino-1,3-dimethyluracil(32970-32-4)

Safety Data

• Hazardous Substances Data: 32970-32-4(Hazardous Substances Data)

Usage

General Description

5-Acetyl-6-amino-1,3-dimethyluracil is a chemical compound with the molecular formula C8H10N4O2. It is a derivative of uracil and belongs to the class of heterocyclic compounds. 5-Acetyl-6-amino-1,3-dimethyluracil is often used as a building block in the synthesis of pharmaceuticals and agrochemicals. It has been found to exhibit antiviral and antitumor activities, making it a potential candidate for drug development. Its structure and properties make it suitable for various chemical reactions and modifications, allowing for its use in a wide range of applications in the pharmaceutical and chemical industries.

InChI:InChI=1/C8H11N3O3/c1-4(12)5-6(9)10(2)8(14)11(3)7(5)13/h9H2,1-3H3

Upstream product

• 6642-31-5 6-Amino-1,3-dimethylbarbituric acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 65183-48-4 3,5,7-trimethylisoxazolo<3,4-d>pyrimidine-4,6(5H,7H)-dione 

Relevant articles and documents

Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding

Human prolyl hydroxylases are involved in the modification of transcription factors, procollagen, and ribosomal proteins, and are current medicinal chemistry targets. To date, there are few reports on inhibitors selective for the different types of prolyl hydroxylases. We report a structurally informed template-based strategy for the development of inhibitors selective for the human ribosomal prolyl hydroxylase OGFOD1. These inhibitors did not target the other human oxygenases tested, including the structurally similar hypoxia-inducible transcription factor prolyl hydroxylase, PHD2.

Studies on the acylation of some 6-aminouracil derivatives.

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