32975-59-0 Usage
Description
N-Benzyl (S)-β-(CarboxyaMino)-hydrocinnaMic Acid Methyl Ester, also known as (S)-β-[[(Phenylmethoxy)carbonyl]amino]-benzenepropanoic Acid Methyl Ester (CAS# 32975-59-0), is a synthetic organic compound with a unique molecular structure. It features a benzyl group attached to a hydrocinnamic acid backbone, with a carboxyamino functionality and a methyl ester group. N-Benzyl (S)-β-(CarboxyaMino)-hydrocinnaMic Acid Methyl Ester is characterized by its potential reactivity and versatility in chemical reactions, making it a valuable intermediate in organic synthesis.
Uses
Used in Pharmaceutical Industry:
N-Benzyl (S)-β-(CarboxyaMino)-hydrocinnaMic Acid Methyl Ester is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications, such as antibiotics, anti-inflammatory agents, and analgesics.
Used in Organic Synthesis:
In the field of organic synthesis, N-Benzyl (S)-β-(CarboxyaMino)-hydrocinnaMic Acid Methyl Ester serves as a versatile building block for the creation of complex organic molecules. Its reactivity and functional groups enable chemists to perform a wide range of reactions, such as amide coupling, esterification, and transesterification, to construct diverse molecular architectures.
Used in Research and Development:
N-Benzyl (S)-β-(CarboxyaMino)-hydrocinnaMic Acid Methyl Ester is also utilized in research and development settings, where it can be employed to study the properties and reactivity of similar molecules. Researchers can use N-Benzyl (S)-β-(CarboxyaMino)-hydrocinnaMic Acid Methyl Ester to investigate new synthetic routes, reaction mechanisms, and the development of novel catalysts or reagents.
Used in Material Science:
N-Benzyl (S)-β-(CarboxyaMino)-hydrocinnaMic Acid Methyl Ester can be incorporated into the design and synthesis of new materials, such as polymers, coatings, and adhesives. Its functional groups and molecular structure can contribute to the development of materials with improved properties, such as enhanced stability, adhesion, or biocompatibility.
Check Digit Verification of cas no
The CAS Registry Mumber 32975-59-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,9,7 and 5 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 32975-59:
(7*3)+(6*2)+(5*9)+(4*7)+(3*5)+(2*5)+(1*9)=140
140 % 10 = 0
So 32975-59-0 is a valid CAS Registry Number.
32975-59-0Relevant articles and documents
Multicomponent Catalytic Enantioselective Synthesis of Isoxazolidin-5-Ones
Annibaletto, Julien,Brière, Jean-Fran?ois,Levacher, Vincent,Martzel, Thomas,Oudeyer, Sylvain
, p. 4447 - 4451 (2021/08/09)
We report herein a strategy to afford a multicomponent catalytic enantioselective synthesis of β-substituted isoxazolidin-5-ones via a KMC process promoted by a suited cupreine used as bifunctional organocatalyst. The hydroxamic acid component, with a ste
Efficient synthesis of β'-amino-α, β-unsaturated ketones
Abrunhosa-Thomas, Isabelle,Plas, Aurelie,Kandepedu, Nishanth,Chalard, Pierre,Troin, Yves
, p. 486 - 495 (2013/04/23)
A general and simple procedure to access chiral β'-amino-α, β-enones, in seven steps, from an α,β unsaturated ester has been described. The use of a Horner-Wadsworth-Emmons reaction as a key step for generating the β'-amino-α,β-enones, permits access to a range of substrates under mild conditions and in moderate to high yield.
Stereoselective synthesis and in vivo evaluation of the analgesic activity of polysubstituted bispidines
Plas, Aurelie,Troin, Yves,Chalard, Pierre,Marchand, Fabien,Eschalier, Alain
, p. 6070 - 6079,10 (2020/09/02)
Hetero-Michael addition on a chiral β'-amino α,β- unsaturated ketone gave, after some structural modifications, β,β'-diamino ketals. Mannich-type reactions of these diamines with an aldehyde led, with high diastereoselectivity, to trisubstituted piperidines. Another highly stereoselective Mannich cyclization, with an N-acyliminium ion generated in situ from the corresponding imide, allowed the preparation of original polycyclic bispidine derivatives. The antinociceptive effect of the three compounds prepared was evaluated in vivo by using the writhing test. If the biological results for the analgesic properties were disappointing, compared with the bispidine HZ2, which has a high affinity for opioid receptors, the modularity of the approach offered the possibility of introducing many substituents for new applications, which was promising because the bispidine core has been described to have many different activities. Total stereoselective synthesis of bispidine derivatives is achieved by using as two successive Mannich reactions key steps. This process constitutes a powerful approach toward the preparation of a polycyclic bispidine backbone with high enantioselectivity.
