329912-53-0

Basic information

• Product Name: (3S,5R)-[5-(benzyloxycarbonylaminomethyl)-2-oxotetrahydrofuran-3-yl]carbamic acid tert-butyl ester
• Synonyms: (3S,5R)-[5-(benzyloxycarbonylaminomethyl)-2-oxotetrahydrofuran-3-yl]carbamic acid tert-butyl ester
• CAS NO: 329912-53-0
• Molecular Weight: 364.398
• Mol File: 329912-53-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (3S,5R)-[5-(benzyloxycarbonylaminomethyl)-2-oxotetrahydrofuran-3-yl]carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,5R)-[5-(benzyloxycarbonylaminomethyl)-2-oxotetrahydrofuran-3-yl]carbamic acid tert-butyl ester(329912-53-0)
• EPA Substance Registry System: (3S,5R)-[5-(benzyloxycarbonylaminomethyl)-2-oxotetrahydrofuran-3-yl]carbamic acid tert-butyl ester(329912-53-0)

Safety Data

• Hazardous Substances Data: 329912-53-0(Hazardous Substances Data)

Upstream product

• 128427-10-1 (S)-2-(tert-butoxycarbonylamino)-1,4-butanediol 
• 128427-09-8 (S)-N-tert-butoxycarbonyl-aspartic acid diethyl ester 
• 371972-14-4 tert-butyl-(2S,4R)-N^α-(tert-butoxycarbonyl)-N^δ-(benzyloxycarbonyl)-4-hydroxy-ornithinate 
• 2899-57-2 Sphenyl N-benzyloxycarbonylaminoethanothioate 
• 147959-19-1 (4S)-2,2-dimethyl-3-(t-butoxycarbonyl)-4-(formylmethyl)-1,3-oxazolidine 
• 147959-18-0 (4S)-2,2-dimethyl-4-(2-hydroxyethyl)oxazolidine-3-carboxylic acid tert-butyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 850996-90-6 (4S)-[(2R)-3-benzyloxycarbonylamino-2-triisopropylsilanyloxypropyl]-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 
• 850996-92-8 (2S,4R)-1-hydroxy-4-triisopropylsilanyloxy-5-benzyloxycarbonylaminopent-2-ylaminocarboxylic acid tert-butyl ester 
• 850996-87-1 (4S)-4-[2-(1-methoxy-1-methylethoxy)ethyl]-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 
• 128075-94-5 (R)-5-{[(tert-butyldiphenylsilyl)oxy]methyl}dihydrofuran-2(3H)-one 
• 135582-85-3 (2S,4R)-2-tert-butoxycarbonylamino-4-azidomethyl-4-butanolide 
• 104241-32-9 (2S,4R)-2-tert-butoxycarbonylamino-4-hydroxymethyl-4-butanolide 
• 6893-26-1 D-Glutamic acid 

Downstream Products

• 135582-94-4 (R)-3-benzyloxycarbonyl-5-<(S)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl)ethyl>-2,2-dimethyl-1,3-oxazolidine 
• 911225-68-8 methyl (2S,4R)-5-benzyloxycarbonylamino-2-tert-butoxycarbonylamino-4-hydroxypentanoate 

Relevant articles and documents

Antibacterial amide macrocycles

The invention relates to antibacterial amide macrocycles, to methods for the production thereof, and to the use of the same for producing pharmaceuticals for the treatment and/or prophylaxis of illness, especially bacterial infections.

IMPROVED PROCEDURE FOR THE PREPARATION OF (4S)- OR (4R)-2,2-DIMETHYL-4-(2-HYDROXETHYL)OXAZOLIDINE-3-CARBOXYLIC ACID ALKYL ESTERS

The present invention is directed to a process for the preparation of (4S)- or (4R)-2,2-dimethyl-4-(2-hydroxethyl)oxazolidine-3-carboxylic acid alkyl esters. The invention is further directed to an intermediate product from which those alkyl esters may be obtained.

Asymmetric synthesis of orthogonally protected (2S,4R)- and (2S,4S)-4-hydroxyornithine

Synthesis of orthogonally protected (2S, 4R)- and (2S, 4S)-4-hydroxyornithine was reported featuring an asymmetric alkylation of N-(diphenylmethylene)glycine tert-butyl ester (6) by (5S)-N-benzyloxycarbonyl-5-iodomethyl oxazolidine (7). Double stereoselection was examined using chiral ammonium salts as phase transfer catalysts and a substrate-directed chiral induction is documented.