330-69-8

Basic information

• Product Name: 1-benzyl-1-methylguanidine hydrochloride (1:1)
• Synonyms: CHEMBRDG-BB 4015994;N-BENZYL-N-METHYLGUANIDINE
• CAS NO: 330-69-8
• Molecular Formula: C₉H₁₃N₃*ClH
• Molecular Weight: 199.6806
• Mol File: 330-69-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 122.5-125.5 °C
• Boiling Point: 270.1°C at 760 mmHg
• Flash Point: 117.1°C
• Vapor Pressure: 0.00699mmHg at 25°C
• CAS DataBase Reference: 1-benzyl-1-methylguanidine hydrochloride (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-1-methylguanidine hydrochloride (1:1)(330-69-8)
• EPA Substance Registry System: 1-benzyl-1-methylguanidine hydrochloride (1:1)(330-69-8)

Safety Data

• Hazardous Substances Data: 330-69-8(Hazardous Substances Data)

Upstream product

• 4023-02-3 1H-pyrazole-1-carboximidamide hydrochloride 
• 103-67-3 benzyl-methyl-amine 

Downstream Products

• 802916-50-3 C₁₅H₁₇N₃O₃ 

Relevant articles and documents

Discovery and structure-activity relationships of trisubstituted pyrimidines/pyridines as novel calcium-sensing receptor antagonists

The trisubstituted pyrimidine 1 was identified through high-throughput screening as a novel calcium-sensing receptor (CaSR) antagonist. Small molecule CaSR antagonists and/or negative allosteric modulators have the potential to act as an anabolic agent for the treatment of osteoporosis. The investigation of structure-activity relationships around 1 resulted in the identification of 18c and 18d, which showed efficacy at promoting PTH release in vivo and exhibited improved potency and solubility over the original lead 1.