330-93-8

Basic information

• Product Name: BIS(4-FLUOROPHENYL) ETHER
• Synonyms: 4,4'-DIFLUORODIPHENYL ETHER;4-FLUOROPHENYL ETHER;BIS(4-FLUOROPHENYL) ETHER;1-Fluoro-4-(4-fluorophenoxy)benzene;Benzene, 1,1'-oxybis[4-fluoro-;Bis(p-fluorophenyl) ether;1,1'-oxybis(4-fluorobenzene);Bis(4-fluorophenyl)ether 97%
• CAS NO: 330-93-8
• Molecular Formula: C₁₂H₈F₂O
• Molecular Weight: 206.19
• EINECS: 206-358-6
• Product Categories: Fluorine series
• Mol File: 330-93-8.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 250 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.23 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.537(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 2559168
• CAS DataBase Reference: BIS(4-FLUOROPHENYL) ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(4-FLUOROPHENYL) ETHER(330-93-8)
• EPA Substance Registry System: BIS(4-FLUOROPHENYL) ETHER(330-93-8)

Safety Data

• Hazard Codes: Xi
• Statements: 34
• Safety Statements: 26-36/37/39-24/25
• RIDADR: 3265
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 330-93-8(Hazardous Substances Data)

Usage

General Description

Bis(4-fluorophenyl) ether is a chemical compound that consists of two 4-fluorophenyl groups connected by an oxygen atom. It is commonly used as a building block in the synthesis of various organic compounds, particularly in the field of medicinal and pharmaceutical chemistry. BIS(4-FLUOROPHENYL) ETHER is known for its high thermal stability and resistance to chemical degradation, making it useful in the development of durable materials and coatings. Bis(4-fluorophenyl) ether has also been studied for its potential use as a flame retardant and as an additive in polymers to improve their fire resistance properties. Additionally, it has shown promise as an antioxidant in certain applications. However, like many chemicals, it should be handled and used with proper precautions to ensure safety and environmental protection.

Upstream product

• 101-80-4 4,4'-oxydiphenylene diamine 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 371-41-5 4-Fluorophenol 
• 1765-93-1 4-fluoroboronic acid 
• 352-34-1 4-fluoro-1-iodobenzene 
• 18840-04-5 trimethyl(4-fluorophenoxy)silane 
• 732306-64-8 bis(4-fluorophenyl)iodonium triflate 

Downstream Products

• 26619-98-7 2,8-difluoro-10-oxo-10H-10λ⁵-phenoxaphosphin-10-ol; dicyclohexylamine salt 
• 71-43-2 benzene 
• 108-95-2 phenol 
• 31708-14-2 1-cyclohexyl-1H-pyrrole 
• 4096-21-3 N-phenylpyrrolidine 
• 1821-36-9 N-phenyl-2-cyclohexylamine 
• 110-82-7 cyclohexane 
• 371-41-5 4-Fluorophenol 

Relevant articles and documents

Organic long-afterglow compound, and preparation method and application thereof

The invention discloses an organic long-afterglow compound, and a preparation method and application thereof, and belongs to the technical field of photodynamic therapy. According to the invention, the long-afterglow compound with a brand-new structure is designed and synthesized on the basis of oxygen group elements. The long-afterglow compound has the following advantages: 1, the imaging time islong, and nanosecond-grade imaging of traditional fluorescent imaging agents is improved to millisecond-imaging of the organic long-afterglow material; 2, the oxygen group elements are introduced into the long-afterglow compound, so that the yield of triplet excitons of molecules is introduced, and generation of reactive oxygen is promoted; 3, the excitation range of the long-afterglow compound can be extended to visible light, and the long-afterglow compound can easily achieve a good therapeutic effect under visible light irradiation and has low biological toxicity; and 4, the long-afterglowcompound has good biocompatibility. According to the invention, experiments prove that the compound has obvious inhibitory activity on Gram-positive bacteria, and thus the compound has a potential for being used as a photosensitizer for effective photodynamic therapy.

Synthesis of copper nanoparticles supported on a microporous covalent triazine polymer: An efficient and reusable catalyst for O-arylation reaction

Copper nanoparticles were supported on a microporous covalent triazine polymer prepared by the Friedel-Crafts reaction (Cu@MCTP-1). The resulting material was characterized by powder X-ray diffraction, thermogravimetric analysis, N2 adsorption-desorption isotherms at 77 K, transmission electron microscopy, X-ray photoelectron spectroscopy, and inductively coupled plasma optical emission spectroscopy, and Cu particles with an average size of 3.0 nm and a BET total surface area of ca. 1002 m2 g-1 were obtained. Cu@MCTP-1 was evaluated as a heterogeneous catalyst for the Ullmann coupling of O-arylation over a series of aryl halides and phenols without employing expensive ligands or inert atmosphere, which produced an excellent yield of the corresponding diaryl ethers. The catalyst could be recovered by simple centrifugation and was reusable at least five times with only a slight decrease in catalytic activity.

Copper(I) Phenoxide complexes in the etherification of aryl halides

"Chemical Equation Presented" No copping out! Copper(I) phenoxide complexes containing chelating ligands (see picture), proposed intermediates in copper-catalyzed etherification of aryl halides, have been synthesized and fully characterized. The kinetic and chemical competence of the isolated complexes are demonstrated for the synthesis of aryl phenyl ethers, and experiments provide evidence against mechanistic pathways involving the formation of either free or caged radicals.