330460-79-2

Basic information

• Product Name: 1-(pyridin-2-yl)ethyl benzoate
• Synonyms: 1-(pyridin-2-yl)ethyl benzoate
• CAS NO: 330460-79-2
• Molecular Weight: 227.263
• Mol File: 330460-79-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(pyridin-2-yl)ethyl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(pyridin-2-yl)ethyl benzoate(330460-79-2)
• EPA Substance Registry System: 1-(pyridin-2-yl)ethyl benzoate(330460-79-2)

Safety Data

• Hazardous Substances Data: 330460-79-2(Hazardous Substances Data)

Upstream product

• 100-71-0 2-Ethylpyridine 
• 65-85-0 benzoic acid 
• 4833-24-3 2-ethylpyridine 1-oxide 
• 100-52-7 benzaldehyde 
• 1122-62-9 2-acetylpyridine 
• 20988-55-0 1-(pyridine-2-yl)ethanol 
• 98-88-4 benzoyl chloride 

Downstream Products

• 59042-90-9 (1S)-1-(2-pyridyl)ethanol 
• 27911-63-3 (R)-1-(2'-pyridyl)ethanol 

Relevant articles and documents

Ligand-Free Copper(I)-Catalyzed Benzylic Acyloxylation of 2-Alkylpyridines under Aerobic Conditions

A ligand-free copper(I)-catalyzed benzylic acyloxylation of 2-alkylpyridines with carboxylic acids was realized by using 1.0 atm of O2 as a green oxidant. The transformation provided a facile access to a wide range of N-heterocyclic esters thro

The importance of ester and alkoxy type functionalities for the chemo- And enantio-recognition of substrates by hydrolysis with Candida rugosa lipase

Racemic esters of 1-phenyl- and 1-(pyridyl)ethyl acetates 1a-c (R = Me, Ph) were subjected to hydrolysis in water in the presence of Candida rugosa lipase (CRL). 1-Pyridylethyl acetates (1, R = Me) are hydrolyzed by crude CRL (C-CRL) and isopropanol (isopropyl alcohol) treated CRL (PT-CRL) at very low rates, and the enantiorecognition was disappointing. By using 1-pyridylethyl benzoates (1, R = Ph) the results differed greatly: hydrolysis occurred much faster, and the enantiorecognition was good for 3- and 4-pyridyl derivatives and excellent for 2-pyridyl derivative. Analogous results were obtained by submitting the 1-phenylethanol esters 4 to enzymatic hydrolysis under the same experimental conditions. The hydrolysis of methyl o-acetoxybenzoates 7 (R = Me) gave quantitatively the deacetylated methyl o-hydroxybenzoates 9 (R = Me) by using either C-CRL or PT-CRL. A complete reversed selectivity is observed in the hydrolysis of phenyl o-acetoxybenzoates 7 (R = Ph) catalyzed by PT-CRL. Molecular modeling studies, aimed at probing the substrate specificity and the enantioselectivity of enzyme in terms of its three-dimensional structure is reported. The Royal Society of Chemistry 2000.