330793-45-8

Basic information

• Product Name: (4-PHENYLAMINOCARBONYLPHENYL)BORONIC ACID
• Synonyms: 4-(PHENYLAMINOCARBONYL)BENZENEBORONIC ACID;(4-PHENYLAMINOCARBONYLPHENYL)BORONIC ACID;N-PHENYL 4-BORONOBENZAMIDE;4-(Phenylaminocarbonyl)benzeneboronic acid 97%;4-PhenylcarbaMoylbenzeneboronic acid, 97%;(4-(PhenylcarbaMoyl)phenyl)boronic acid;4-(Phenylaminocarbonyl)benzeneboronicacid97%
• CAS NO: 330793-45-8
• Molecular Formula: C₁₃H₁₂BNO₃
• Molecular Weight: 241.05
• Product Categories: blocks;BoronicAcids
• Mol File: 330793-45-8.mol
• Article Data: 9

Chemical Properties

• Melting Point: 210-216°C
• Appearance: /
• Density: 1.281 g/cm³
• Refractive Index: 1.623
• Storage Temp.: Keep Cold
• PKA: 8.33±0.17(Predicted)
• CAS DataBase Reference: (4-PHENYLAMINOCARBONYLPHENYL)BORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (4-PHENYLAMINOCARBONYLPHENYL)BORONIC ACID(330793-45-8)
• EPA Substance Registry System: (4-PHENYLAMINOCARBONYLPHENYL)BORONIC ACID(330793-45-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 330793-45-8(Hazardous Substances Data)

Usage

General Description

(4-Phenylaminocarbonylphenyl)boronic acid is an organoboronic acid compound with the chemical formula C18H16BNO3. It is commonly used in organic synthesis and as a building block for the preparation of various pharmaceuticals, agrochemicals, and organic materials. Due to its boronic acid functional group, it can be used as a reagent in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds. (4-PHENYLAMINOCARBONYLPHENYL)BORONIC ACID has potential applications in the development of new drugs and materials, as well as in the synthesis of complex organic molecules for various industrial purposes.

InChI:InChI=1/C13H12BNO3/c16-13(15-12-4-2-1-3-5-12)10-6-8-11(9-7-10)14(17)18/h1-9,17-18H,(H,15,16)

Upstream product

• 14047-29-1 4-carboxyphenylboronic acid 
• 62-53-3 aniline 
• 109-72-8 n-butyllithium 
• 330793-39-0 N₁-phenyl-4-bromo-2-methoxybenzamide 
• 5419-55-6 Triisopropyl borate 

Relevant articles and documents

Discovery of thieno[3,2-c]pyridin-4-amines as novel Bruton's tyrosine kinase (BTK) inhibitors

A novel series of BTK inhibitors bearing thieno[3,2-c]pyridin-4-amine framework as the core scaffold were designed, synthesized and well characterized. In this paper, twenty one compounds displayed variant inhibitory activities against BTK in vitro, and c

Thieno [3, 2 - c] pyridine compound, its preparation method and application

The invention relates to a thieno-[3,2-c] pyridine type compound and an application thereof. The compound has a structure shown by a formula (I) in the specification. The compound of which the structure is shown by the formula (I), provided by the invention has a very good effect of inhibiting the activity of Bruton kinase. The invention also relates to the application of the compound in preventing and/or treating diseases which are improved by virtue of BTK (Bruton tyrosine kinase) activity inhibition.

Pyrazolopyrimidines as therapeutic agents

The present invention is directed to pyrazolopyrimidine derivatives of formula (I) wherein the substituents are defined herein, which are useful as kinase inhibitors and as such are useful for affecting angiogenesis and diseases and conditions associated with angiogenesis.