330945-23-8 Usage
Common use
Pharmaceutical research and drug development
Type
Fluorinated derivative of pyrrolidinedicarboxylic acid
Potential therapeutic properties
Exhibited in various diseases and medical conditions
Stereochemistry
(2R,3S)prefix indicates the arrangement of atoms in three-dimensional space
Effects of stereochemistry
Can have significant effects on biological activity and pharmacokinetics
Potential applications
Treatment of various diseases and medical conditions
Importance
Holds promise as a valuable tool in the development of new and improved medications
Check Digit Verification of cas no
The CAS Registry Mumber 330945-23-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,0,9,4 and 5 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 330945-23:
(8*3)+(7*3)+(6*0)+(5*9)+(4*4)+(3*5)+(2*2)+(1*3)=128
128 % 10 = 8
So 330945-23-8 is a valid CAS Registry Number.
330945-23-8Relevant articles and documents
3S-Fluoroproline as a probe to monitor proline isomerization during protein folding by 19F-NMR
Thomas, Colin A.,Talaty, Erach R.,Bann, James G.
supporting information; experimental part, p. 3366 - 3368 (2009/12/26)
Variable-temperature inversion transfer NMR is used to determine the kinetic and thermodynamic parameters of cis-trans isomerization of N-Ac-(3R) and (3S)-fluoroproline-OMe.
Synthesis of optically pure N-Boc-protected (2R,3R)- and (2R,3S)-3-fluoroprolines
Demange, Luc,Cluzeau, Jér?me,Ménez, André,Dugave, Christophe
, p. 651 - 653 (2007/10/03)
Non-protein amino acids (2R,3R)- and (2R,3S)-3-fluoroprolines were synthesized as novel probes for studying the cis/trans isomerization of the amino acyl-proline peptide bond. The N-Boc-protected target compounds were obtained as optically pure material s
