3312-60-5 Usage
Description
N-(3-Aminopropyl)cyclohexylamine is a colorless to light yellow liquid that serves as a competitive inhibitor of spermine and spermidine synthases, which are enzymes involved in the biosynthesis of polyamines. These polyamines play crucial roles in various cellular processes, including cell growth, proliferation, and gene expression.
Uses
Used in Pharmaceutical Industry:
N-(3-Aminopropyl)cyclohexylamine is used as a pharmaceutical compound for its ability to inhibit spermine and spermidine synthases. By targeting these enzymes, it can potentially disrupt the biosynthesis of polyamines, which may have therapeutic applications in conditions where the overproduction of these molecules contributes to disease progression.
Used in Research Applications:
In the field of research, N-(3-Aminopropyl)cyclohexylamine is used as a tool to study the role of polyamines in various cellular processes. By inhibiting the enzymes responsible for their synthesis, researchers can gain insights into the mechanisms by which these molecules influence cell growth, proliferation, and gene expression.
Used in Drug Development:
N-(3-Aminopropyl)cyclohexylamine may also be utilized in the development of new drugs targeting polyamine metabolism. By understanding the effects of this compound on spermine and spermidine synthases, researchers can potentially design more effective therapeutic agents for conditions where polyamine dysregulation is implicated.
Check Digit Verification of cas no
The CAS Registry Mumber 3312-60-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,1 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3312-60:
(6*3)+(5*3)+(4*1)+(3*2)+(2*6)+(1*0)=55
55 % 10 = 5
So 3312-60-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H20N2/c10-7-4-8-11-9-5-2-1-3-6-9/h9,11H,1-8,10H2
3312-60-5Relevant articles and documents
INHIBITORS OF BACTERIAL GLYCOSYL TRANSFERASES
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Paragraph 00370; 00429, (2016/12/22)
Described herein are compounds of Formula (I'), Formula (IA), Formulae (I)-(VII), pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrug sthereof. The invention also provides pharmaceutical compositions of the compounds for human and veterinary use. Compounds of the present invention are useful for inhibiting bacterial growth and therefore are useful in treating and/or preventing bacterial infections. Methods of using the compounds for treating and/or preventing a bacterial infection in a subject are also described.
Tert-Butylsulfonyl (Bus), a New Protecting Group for Amines
Sun, Pu,Weinreb, Steven M.,Shang, Maoyu
, p. 8604 - 8606 (2007/10/03)
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THE HYPOTENSIVE ACTIVITY OF N-CYCLOHEXYL AND N-METHYL DERIVATIVES OF
SHORT,CHAN,FREIFELDER,MIKOLASEK,SCHMIDT,SCHOEPKE,SHANNON,STONE
, p. 596 - 598 (2007/10/05)
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