33173-27-2 Usage
Description
(S)-3-(4-nitrophenyl)-2-hydroxypropionic acid is a chiral chemical compound with the molecular formula C9H9NO6. It features a 4-nitrophenyl group attached to a 2-hydroxypropionic acid backbone, which endows it with unique chemical and biological properties. As a chiral molecule, it exists in two mirror-image forms known as enantiomers. (S)-3-(4-nitrophenyl)-2-hydroxypropionic acid is widely utilized in organic synthesis and chemical research for constructing more complex molecules, taking advantage of the electron-withdrawing nature of the 4-nitrophenyl group, which makes it a valuable component in reactions requiring strong electrophilic substituents. Additionally, (S)-3-(4-nitrophenyl)-2-hydroxypropionic acid may exhibit various biological activities, positioning it as a potential candidate for pharmaceutical research in drug discovery and development.
Uses
Used in Organic Synthesis:
(S)-3-(4-nitrophenyl)-2-hydroxypropionic acid is used as a building block in organic synthesis for the creation of more complex molecules. Its 4-nitrophenyl group provides electron-withdrawing capabilities, making it a useful component in reactions that necessitate strong electrophilic substituents.
Used in Chemical Research:
In chemical research, (S)-3-(4-nitrophenyl)-2-hydroxypropionic acid serves as an essential compound for studying various reaction mechanisms and exploring new synthetic pathways. Its unique structure allows researchers to investigate its properties and reactivity, contributing to the advancement of chemical knowledge.
Used in Pharmaceutical Research:
(S)-3-(4-nitrophenyl)-2-hydroxypropionic acid is used as a potential candidate in pharmaceutical research for drug discovery and development. Its possible biological activities make it an interesting starting point for the design and synthesis of new therapeutic agents.
Used in Drug Delivery Systems:
In the pharmaceutical industry, (S)-3-(4-nitrophenyl)-2-hydroxypropionic acid may be employed in the development of novel drug delivery systems. Its unique properties could be harnessed to improve the delivery, bioavailability, and therapeutic outcomes of various drugs, particularly in the context of targeted drug delivery and controlled release applications.
Used in Analytical Chemistry:
(S)-3-(4-nitrophenyl)-2-hydroxypropionic acid can be utilized in analytical chemistry as a reagent or a reference compound for the development and validation of analytical methods. Its distinct chemical and physical properties make it suitable for various applications, such as chromatography, spectroscopy, and titration techniques.
Check Digit Verification of cas no
The CAS Registry Mumber 33173-27-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,1,7 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 33173-27:
(7*3)+(6*3)+(5*1)+(4*7)+(3*3)+(2*2)+(1*7)=92
92 % 10 = 2
So 33173-27-2 is a valid CAS Registry Number.
33173-27-2Relevant articles and documents
Synthesis and evaluation of some novel isochroman carboxylic acid derivatives as potential anti-diabetic agents
Lakshminarayana,Rajendra Prasad,Gharat, Laxmikant,Thomas, Abraham,Ravikumar,Narayanan, Shridhar,Srinivasan,Gopalan, Balasubramanian
experimental part, p. 3147 - 3157 (2009/12/04)
A series of novel isochroman mono-carboxylic acid derivatives were synthesized, characterized and evaluated for their ability to inhibit protein tyrosine phosphatase 1B (PTP1B) in vitro in order to use them as potential anti-diabetic agents. Analysis of structure-activity relationships led to the identification of potent compound 4n which inhibited PTP1B with IC50 value of 51.63 ± 0.91 nM. In general, high potency was associated with a dithiolane ring with a spacer of five carbons to the isochroman ring. Compound 4n has been selected for in vivo evaluation as drug candidate for anti-diabetic activity.
Biocatalytic racemization of (hetero)aryl-aliphatic α- hydroxycarboxylic acids by Lactobacillus spp. proceeds via an oxidation-reduction sequence
Nestl, Bettina M.,Glueck, Silvia M.,Hall, Melanie,Kroutil, Wolfgang,Stuermer, Rainer,Hauer, Bernhard,Faber, Kurt
, p. 4573 - 4577 (2007/10/03)
The biocatalytic racemization of a range of (hetero)aryl- and (di)aryl-aliphatic α-hydroxycarboxylic acids has been achieved by using whole resting cells of Lactobacillus spp. The essentially mild (physiological) reaction conditions ensure the suppression of undesired side reactions, such as elimination, decomposition or condensation. Cofactor/inhibitor studies using a cell-free extract of Lactobacillus paracasei DSM 20207 reveal that the addition of redox cofactors (NAD+/NADH) leads to a distinct increase in the racemization rate, while strong inhibition is observed in the presence of Thio-NAD+, which suggests that the racemization proceeds by an oxidation-reduction sequence rather than involvement of a "racemase" enzyme. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.
NOVEL COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
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Page/Page column 59-60, (2010/02/11)
The present invention relates to novel compounds of formula (I) and their pharmaceutically acceptable salts thereof, pharmaceutical compositions containing them. The present invention also relates to a process for the preparation of the above said novel compounds.
