331949-29-2Relevant articles and documents
Synthesis of 5/7-, 5/8- And 5/9-bicyclic lactam templates as constraints for external β-turns
Duggan, Heather M. E.,Hitchcock, Peter B.,Young, Douglas W.
, p. 2287 - 2295 (2007/10/03)
The 5/7-, 5/8- and 5/9-bicyclic lactams 3, 17, 5 and 6 have been synthesised as single diastereoisomers by a route involving ring closing olefin metathesis. The X-ray crystal structure of the amino acid hydrochloride 17 has been carried out and compared t
Carbapenem biosynthesis: Confirmation of stereochemical assignments and the role of CarC in the ring stereoinversion process from L-Proline
Stapon, Anthony,Li, Rongfeng,Townsend, Craig A.
, p. 8486 - 8493 (2007/10/03)
(5R)-Carbapen-2-em-3-carboxylic acid is the simplest structurally among the naturally occurring carbapenem β-lactam antibiotics. It co-occurs with two saturated (3S,5S)- and (3S,5R)-carbapenam carboxylic acids. Confusion persists in the literature about t
Improved synthesis of (2S,5S)-5-tert-butylproline
Halab, Liliane,Bélec, Laurent,Lubell, William D
, p. 6439 - 6446 (2007/10/03)
(2S,5S)-N-Boc-5-tert-butylproline (1) was synthesized by an improved procedure featuring the conversion of (2S)-1-tert-butyldimethylsiloxy-2-N-(PhF)amino-5-oxo-6,6-dimethylheptane (16) into its corresponding imino alcohol followed by directed hydride deli